药理学走钢丝:利培酮在啼哭综合征中的平衡作用。

Quamaine Bond, Himanshu Agrawal
{"title":"药理学走钢丝:利培酮在啼哭综合征中的平衡作用。","authors":"Quamaine Bond, Himanshu Agrawal","doi":"10.1007/s44192-024-00094-1","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>This case report describes an infrequent instance of risperidone-induced hyperprolactinemia in a 23-year-old nonverbal male with cri du chat syndrome.</p><p><strong>Case presentation: </strong>Risperidone, initially prescribed to manage aggressive behaviors, resulted in bilateral gynecomastia and hyperprolactinemia. Tapering of risperidone led to resolution of these symptoms but exposed a resurgence of excessive masturbation, a behavior previously suppressed by the medication. Reintroduction of risperidone controlled this behavior, suggesting its potential role in managing compulsive behaviors in this population.</p><p><strong>Conclusion: </strong>This case underscores the complex interaction between pharmacological treatment and behavioral symptoms in neurodevelopmental disorders. It highlights the necessity for meticulous monitoring and individualized treatment approaches in managing such cases.</p><p><strong>Case presentation: </strong>Initially prescribed for managing aggressive behaviors, Risperidone led to bilateral gynecomastia and hyperprolactinemia in the patient. Gradual tapering of Risperidone alleviated these symptoms but unveiled a resurgence of excessive masturbation, a behavior previously suppressed by the medication. Reintroduction of Risperidone mitigated this behavior, suggesting its potential efficacy in managing compulsive tendencies in this demographic.</p><p><strong>Conclusion: </strong>This case highlights the intricate interplay between pharmacological interventions and the complex behavioral manifestations of neurodevelopmental disorders. It underscores the importance of vigilant monitoring and personalized treatment strategies in such cases.</p>","PeriodicalId":72827,"journal":{"name":"Discover mental health","volume":"4 1","pages":"35"},"PeriodicalIF":0.0000,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11387558/pdf/","citationCount":"0","resultStr":"{\"title\":\"Pharmacological tightrope: risperidone's balancing act in cri du chat syndrome.\",\"authors\":\"Quamaine Bond, Himanshu Agrawal\",\"doi\":\"10.1007/s44192-024-00094-1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>This case report describes an infrequent instance of risperidone-induced hyperprolactinemia in a 23-year-old nonverbal male with cri du chat syndrome.</p><p><strong>Case presentation: </strong>Risperidone, initially prescribed to manage aggressive behaviors, resulted in bilateral gynecomastia and hyperprolactinemia. Tapering of risperidone led to resolution of these symptoms but exposed a resurgence of excessive masturbation, a behavior previously suppressed by the medication. Reintroduction of risperidone controlled this behavior, suggesting its potential role in managing compulsive behaviors in this population.</p><p><strong>Conclusion: </strong>This case underscores the complex interaction between pharmacological treatment and behavioral symptoms in neurodevelopmental disorders. It highlights the necessity for meticulous monitoring and individualized treatment approaches in managing such cases.</p><p><strong>Case presentation: </strong>Initially prescribed for managing aggressive behaviors, Risperidone led to bilateral gynecomastia and hyperprolactinemia in the patient. Gradual tapering of Risperidone alleviated these symptoms but unveiled a resurgence of excessive masturbation, a behavior previously suppressed by the medication. Reintroduction of Risperidone mitigated this behavior, suggesting its potential efficacy in managing compulsive tendencies in this demographic.</p><p><strong>Conclusion: </strong>This case highlights the intricate interplay between pharmacological interventions and the complex behavioral manifestations of neurodevelopmental disorders. It underscores the importance of vigilant monitoring and personalized treatment strategies in such cases.</p>\",\"PeriodicalId\":72827,\"journal\":{\"name\":\"Discover mental health\",\"volume\":\"4 1\",\"pages\":\"35\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-09-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11387558/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Discover mental health\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1007/s44192-024-00094-1\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Discover mental health","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s44192-024-00094-1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

背景:本病例报告描述了一名患有啼哭综合征的 23 岁非语言男性因利培酮诱发高泌乳素血症的罕见病例:利培酮最初用于控制攻击行为,结果导致双侧妇科肿瘤和高泌乳素血症。减少利培酮用量后,这些症状得到缓解,但过度手淫的症状再次出现,而这种行为之前一直受到药物抑制。重新使用利培酮后,这种行为得到控制,这表明利培酮在控制这类患者的强迫行为方面具有潜在作用:本病例强调了神经发育障碍患者的药物治疗与行为症状之间复杂的相互作用。结论:本病例强调了药物治疗与神经发育障碍患者行为症状之间复杂的相互作用,突出了在管理此类病例时进行细致监测和采取个性化治疗方法的必要性:利培酮最初用于控制攻击行为,但却导致患者出现双侧妇科肿大和高泌乳素血症。逐渐减量利培酮缓解了这些症状,但过度手淫的症状再次出现,而这种行为之前一直受到药物的抑制。重新使用利培酮后,这种行为有所缓解,这表明利培酮在控制这一人群的强迫倾向方面具有潜在疗效:本病例凸显了药物干预与神经发育障碍复杂行为表现之间错综复杂的相互作用。结论:本病例突出了药物干预与神经发育障碍的复杂行为表现之间错综复杂的相互作用,强调了对此类病例进行警惕性监测和采取个性化治疗策略的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Pharmacological tightrope: risperidone's balancing act in cri du chat syndrome.

Background: This case report describes an infrequent instance of risperidone-induced hyperprolactinemia in a 23-year-old nonverbal male with cri du chat syndrome.

Case presentation: Risperidone, initially prescribed to manage aggressive behaviors, resulted in bilateral gynecomastia and hyperprolactinemia. Tapering of risperidone led to resolution of these symptoms but exposed a resurgence of excessive masturbation, a behavior previously suppressed by the medication. Reintroduction of risperidone controlled this behavior, suggesting its potential role in managing compulsive behaviors in this population.

Conclusion: This case underscores the complex interaction between pharmacological treatment and behavioral symptoms in neurodevelopmental disorders. It highlights the necessity for meticulous monitoring and individualized treatment approaches in managing such cases.

Case presentation: Initially prescribed for managing aggressive behaviors, Risperidone led to bilateral gynecomastia and hyperprolactinemia in the patient. Gradual tapering of Risperidone alleviated these symptoms but unveiled a resurgence of excessive masturbation, a behavior previously suppressed by the medication. Reintroduction of Risperidone mitigated this behavior, suggesting its potential efficacy in managing compulsive tendencies in this demographic.

Conclusion: This case highlights the intricate interplay between pharmacological interventions and the complex behavioral manifestations of neurodevelopmental disorders. It underscores the importance of vigilant monitoring and personalized treatment strategies in such cases.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
1.90
自引率
0.00%
发文量
0
期刊最新文献
Distribution and association of road traffic accident with depression among Indian population aged 45 years and above: nested multilevel modelling analysis of nationally representative cross-sectional survey. Unveiling the burden: prevalence and predictors of psychological distress among domestic workers in Kigali-Rwanda. Patterns and outcomes of individuals admitted at emergency units following intentional self-harm in Northern Uganda. Prevalence of substance use among a sample of patients attending an outpatient psychiatric clinic in Amman, Jordan. The role of emotion regulation strategies as the mediator between self-compassion and depression among undergraduates in Yunnan province, China.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1