微创二尖瓣修复术的存活率和耐久性:不同修复技术的启示

Alessandra Iaccarino, Ilaria Giambuzzi, Denise Galbiati, Enea Cuko, Ginevra Droandi, Sara Forcina, Eraldo Kushta, Alessio Basciu, Alessandro Barbone, Andrea Fumero, Lucia Torracca
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引用次数: 0

摘要

本研究评估了退行性二尖瓣反流患者微创二尖瓣修复术(MIMVR)的长期疗效,重点关注生存率、二尖瓣修复失败率和再次手术率。采用时间到事件方法分析了接受四角形切除术、边缘到边缘修复术和人工腱膜植入术这三种主要修复技术的患者队列。1年、10年和20年的总生存率都很高,而且各种技术的生存率相当,这表明MIMVR的长期疗效显著。然而,与人工腱膜组相比,四角形切除组和边缘对边缘组的中度二尖瓣反流(MR)≥2的复发率明显更高。复发性 MR ≥ 3 的组别无明显差异。所有技术的再手术率都很低且相似,这突出表明了 MIMVR 的耐用性。出院前残余 MR ≥ 2 是预测长期修复失败的一个重要因素。这些研究结果证实了 MIMVR 的有效性,所有技术都表现出了极佳的长期存活率和耐久性。
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Survival and Durability of Minimally Invasive Mitral Valve Repair: Insights from Different Repair Techniques.

This study evaluates the long-term outcomes of minimally invasive mitral valve repair (MIMVR) in patients with degenerative mitral regurgitation, focusing on survival, mitral valve repair failure, and re-operation rates. A cohort of patients undergoing three primary repair techniques-quadrangular resection, edge-to-edge repair, and artificial chordae implantation-was analyzed using time-to-event methods. The overall survival rates at 1, 10, and 20 years were high and comparable among the techniques, indicating effective long-term benefits of MIMVR. However, freedom from recurrence of moderate mitral regurgitation (MR) ≥ 2 was significantly higher in the quadrangular resection and edge-to-edge groups compared to the artificial chordae group. No significant differences were observed for recurrent MR ≥ 3. Re-operation rates were low and similar across all techniques, underscoring the durability of MIMVR. Pre-discharge residual MR ≥ 2 was identified as a strong predictor of long-term repair failure. These findings confirm the effectiveness of MIMVR, with all techniques demonstrating excellent long-term survival and durability.

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