[近距离放射源停留位置对宫颈癌治疗剂量分布的影响]。

Nihon Hoshasen Gijutsu Gakkai zasshi Pub Date : 2024-10-20 Epub Date: 2024-10-02 DOI:10.6009/jjrt.2024-1420
Tadashi Shimamoto, Hiroki Ooura, Toshiki Ono
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引用次数: 0

摘要

目的:研究近距离放射疗法治疗宫颈癌时,不同放射源停留位置对剂量分布的影响:方法:使用宫颈癌患者的治疗计划数据。治疗计划是以 1 毫米的间隔创建的,最大间隔为 5 毫米。对于腔内近距离治疗以及腔内和间质近距离治疗,对以下剂量参数进行了评估:90% 高风险临床靶体积(HR-CTV D90%)、直肠 2 cm3 剂量(直肠 D2 cc)、小肠 2 cm3 剂量(小肠 D2 cc)、乙状结肠 2 cm3 剂量(乙状结肠 D2 cc)、膀胱 2 cm3 剂量(膀胱 D2 cc)、A 点剂量:在腔内近距离放射治疗中,随着放射源停留位置方向的改变,HR-CTV D90%、直肠 D2 cc、小肠 D2 cc 和乙状结肠 D2 cc 的剂量也随之增加。另一方面,当放射源位置向外变化时,膀胱 D2 cc 的剂量增加。在腔内和间质近距离放射治疗中也观察到了同样的趋势:结论:研究表明,放射源停留位置每改变 1 毫米,对剂量的影响可达 2% 或更多。放射源停留位置的准确性非常重要,应在使用设备前进行检查。
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[Effect of Brachytherapy Source Dwell Position on Dose Distribution in Cervical Cancer Therapy].

Purpose: To investigate the effect of different source dwell positions on dose distribution in the treatment of cervical cancer with brachytherapy.

Methods: Treatment planning data for cervical cancer patients were used. Treatment plans were created at 1 mm intervals, varying up to 5 mm. For intracavitary brachytherapy and intracavitary and interstitial brachytherapy, the following dose parameters were evaluated: 90% high-risk clinical target volume (HR-CTV D90%), rectum 2 cm3 dose (Rectum D2 cc), small intestine 2 cm3 dose (Small D2 cc), sigmoid colon 2 cm3 dose (Sigmoid D2 cc), bladder 2 cm3 dose (Bladder D2 cc), point A dose.

Results: In intracavitary brachytherapy, the HR-CTV D90%, Rectum D2 cc, Small D2 cc, and Sigmoid D2 cc doses increased as the source dwell position changed in the direction. On the other hand, the dose of Bladder D2 cc increased when the source position changed in the outward direction. The same trend was observed in the case of intracavitary and interstitial brachytherapy.

Conclusion: It was shown that a 1 mm change in the source dwell position can affect the dose by up to 2% or more. The accuracy of the source dwell position is very important and should be checked before using the device.

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