对比增强超声对良性和恶性附件肿块的诊断价值:一项 Meta 分析。

IF 2.1 4区 医学 Q2 ACOUSTICS Journal of Ultrasound in Medicine Pub Date : 2024-09-24 DOI:10.1002/jum.16580
Boyang Zhang BMed, Xiao Han BMed
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引用次数: 0

摘要

在妇科肿瘤的诊断中,确定附件肿块的良性或恶性是一个关键而复杂的问题。对比增强超声(CEUS)是一种相对新颖的诊断方法,其应用日益广泛。因此,本研究通过荟萃分析和系统综述评估了CEUS在区分附件肿块良性和恶性方面的诊断价值。我们系统检索了PubMed、Embase、Web of Science和Cochrane图书馆截至2024年4月发表的有关使用CEUS诊断良性和恶性附件肿块的研究。使用 STATA 14.0 软件进行数据分析,汇总符合条件的研究的敏感性、特异性、阳性似然比、阴性似然比和诊断几率比(DOR)。经过初步筛选,共确定了 305 项研究,其中 13 项符合纳入标准,并在本次荟萃分析中进行了分析。CEUS诊断良性和恶性附件肿块的集合敏感性、特异性、阳性似然比、阴性似然比和DOR分别为0.92(95% 置信区间[CI]:0.88-0.95)、0.88(95% CI:0.82-0.93)、8.00(95% CI:5.00-12.90)、0.09(95% CI:0.06-0.14)和91.00(95% CI:45.00-185.00)。接收者操作特征曲线下面积(AUC)为 0.95(95% CI:0.93-0.97)。CEUS 是一种无创、无辐射的成像模式,在诊断良性和恶性附件肿块方面具有很高的准确性和可靠性。为了给临床提供有效的辅助工具,未来的研究可以进一步探讨CEUS的具体应用价值及其在不同人群中的表现。
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Diagnostic Value of Contrast-Enhanced Ultrasound in Benign and Malignant Adnexal Masses

In the diagnosis of gynecological tumors, determining the benign or malignant nature of adnexal masses is a crucial and complex issue. Contrast-enhanced ultrasound (CEUS) is a relatively novel and increasingly used diagnostic method. Therefore, this study evaluated the diagnostic value of CEUS in differentiating benign and malignant adnexal masses through meta-analysis and systematic review. We systematically searched PubMed, Embase, Web of Science, and the Cochrane Library for studies published up to April 2024 regarding the use of CEUS in diagnosing benign and malignant adnexal masses. STATA 14.0 software was used for data analysis, pooling the sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, and diagnostic odds ratio (DOR) of eligible studies. After initial screening, 305 studies were identified, 13 of which met the inclusion criteria and were analyzed in this meta-analysis. The pooled sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, and DOR of CEUS for the diagnosis of benign and malignant adnexal masses were 0.92 (95% confidence interval [CI]: 0.88–0.95), 0.88 (95% CI: 0.82–0.93), 8.00 (95% CI: 5.00–12.90), 0.09 (95% CI: 0.06–0.14), and 91.00 (95% CI: 45.00–185.00), respectively. The area under the summary receiver operating characteristic curve (AUC) was 0.95 (95% CI: 0.93–0.97). CEUS is a noninvasive, nonradiative imaging modality with high accuracy and reliability in the diagnosis of benign and malignant adnexal masses. To provide an effective adjunct tool in the clinic, future studies can further explore the specific application value of CEUS and its performance in different populations.

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来源期刊
CiteScore
5.10
自引率
4.30%
发文量
205
审稿时长
1.5 months
期刊介绍: The Journal of Ultrasound in Medicine (JUM) is dedicated to the rapid, accurate publication of original articles dealing with all aspects of medical ultrasound, particularly its direct application to patient care but also relevant basic science, advances in instrumentation, and biological effects. The journal is an official publication of the American Institute of Ultrasound in Medicine and publishes articles in a variety of categories, including Original Research papers, Review Articles, Pictorial Essays, Technical Innovations, Case Series, Letters to the Editor, and more, from an international bevy of countries in a continual effort to showcase and promote advances in the ultrasound community. Represented through these efforts are a wide variety of disciplines of ultrasound, including, but not limited to: -Basic Science- Breast Ultrasound- Contrast-Enhanced Ultrasound- Dermatology- Echocardiography- Elastography- Emergency Medicine- Fetal Echocardiography- Gastrointestinal Ultrasound- General and Abdominal Ultrasound- Genitourinary Ultrasound- Gynecologic Ultrasound- Head and Neck Ultrasound- High Frequency Clinical and Preclinical Imaging- Interventional-Intraoperative Ultrasound- Musculoskeletal Ultrasound- Neurosonology- Obstetric Ultrasound- Ophthalmologic Ultrasound- Pediatric Ultrasound- Point-of-Care Ultrasound- Public Policy- Superficial Structures- Therapeutic Ultrasound- Ultrasound Education- Ultrasound in Global Health- Urologic Ultrasound- Vascular Ultrasound
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