香樟叶提取物的植物化合物谱分析和气相色谱-质谱分析

IF 3.2 4区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY Journal of the Indian Chemical Society Pub Date : 2024-09-16 DOI:10.1016/j.jics.2024.101379
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引用次数: 0

摘要

这项研究的主要目的是对香樟叶的化学成分进行初步分析,重点是确定潜在的药理活性化合物。采用气相色谱-质谱法(GC-MS)对各种叶片提取物进行了初步的植物化学筛选。结果发现了香樟叶中的多种植物成分,包括类固醇、萜类、黄酮类、醌类、碳水化合物、生物碱和酚类。利用气相色谱-质谱对粗水提取物进行的详细分析确定了几种具有生物活性的成分,如 13-二十二烯酰胺、α-羟基异己酸、环(L-脯氨酰-L-缬氨酸)和 2,5-哌嗪二酮等。这些化合物的存在比例各不相同,表明香茶菜叶中的化学成分十分复杂。研究结果表明,这些已发现的化学物质可能有助于提高该植物的药理特性,并具有创新医疗应用的巨大潜力。该植物的生物活性化合物包括吡咯并[1,2-a]吡嗪-1,4-二酮、十六烷酸、六氢和油酸,这些化合物可能具有广泛的治疗功效。这项研究为了解香茶菜的化学成分提供了宝贵的资料,并强调了这些化合物在医学研究中的潜在意义。此外,它还为今后的研究和探索新的制药机会开辟了前景广阔的途径。
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Phytocompound profiling and GC-MS analysis of Lantana camara leaf extract
The primary objective of this investigation was to conduct an initial analysis of the chemical composition of Lantana camara leaves, with a specific focus on identifying potential pharmacologically active compounds. Gas chromatography-mass spectrometry (GC-MS) was employed to perform a preliminary phytochemical screening on various leaf extracts. The results identified multiple classes of phytoconstituents in Lantana camara leaves, including steroids, terpenoids, flavonoids, quinones, carbohydrates, alkaloids, and phenols. A detailed analysis of the crude aqueous extract using GC-MS identified several biologically active components, such as 13-docosenamide, alpha-hydroxyisocaproic acid, cyclo(L-prolyl-L-valine), and 2,5-piperazinedione etc. These compounds were present in varying proportions, indicating a complex chemical composition within the leaves of Lantana camara. The study's findings suggest that these identified chemicals may contribute to the plant's pharmacological properties and hold significant potential for innovative medical applications. The plant's bioactive compounds, including pyrrolo[1,2-a]pyrazine-1,4-dione, hexadecanoic acid, hexahydro and oleic acid, point to a wide range of possible therapeutic benefits. This investigation provides valuable insights into the chemical constituents of Lantana camara and underscores the potential significance of these compounds in medicinal research. Furthermore, it opens up promising avenues for future studies and the exploration of new pharmaceutical opportunities.
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来源期刊
CiteScore
3.50
自引率
7.70%
发文量
492
审稿时长
3-8 weeks
期刊介绍: The Journal of the Indian Chemical Society publishes original, fundamental, theorical, experimental research work of highest quality in all areas of chemistry, biochemistry, medicinal chemistry, electrochemistry, agrochemistry, chemical engineering and technology, food chemistry, environmental chemistry, etc.
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