{"title":"阿斯利康 COVID-19 疫苗接种后继发性 T 细胞缺乏症病例报告","authors":"Amin Esmailian BSC (Hons), MD , Sara Laura Barnes MBBS (Hons), MBA, FRACP, ADJAOP , Marsus Pumar BBiomedSc (Hons), BMBS, MPhil","doi":"10.1016/j.jacig.2024.100339","DOIUrl":null,"url":null,"abstract":"<div><div>We present a case of secondary T-cell deficiency particularly affecting CD4 T cells, along with the emergence of chronic spontaneous urticaria in a patient following COVID-19 vaccination. The condition was partially managed with omalizumab after initial first-line therapy proved ineffective.</div></div>","PeriodicalId":75041,"journal":{"name":"The journal of allergy and clinical immunology. Global","volume":"3 4","pages":"Article 100339"},"PeriodicalIF":0.0000,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772829324001358/pdfft?md5=18984cb165c25986a8596a564a6b8786&pid=1-s2.0-S2772829324001358-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Case report of secondary T-cell deficiency following the AstraZeneca COVID-19 vaccine\",\"authors\":\"Amin Esmailian BSC (Hons), MD , Sara Laura Barnes MBBS (Hons), MBA, FRACP, ADJAOP , Marsus Pumar BBiomedSc (Hons), BMBS, MPhil\",\"doi\":\"10.1016/j.jacig.2024.100339\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>We present a case of secondary T-cell deficiency particularly affecting CD4 T cells, along with the emergence of chronic spontaneous urticaria in a patient following COVID-19 vaccination. The condition was partially managed with omalizumab after initial first-line therapy proved ineffective.</div></div>\",\"PeriodicalId\":75041,\"journal\":{\"name\":\"The journal of allergy and clinical immunology. Global\",\"volume\":\"3 4\",\"pages\":\"Article 100339\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-09-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2772829324001358/pdfft?md5=18984cb165c25986a8596a564a6b8786&pid=1-s2.0-S2772829324001358-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The journal of allergy and clinical immunology. Global\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2772829324001358\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The journal of allergy and clinical immunology. Global","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2772829324001358","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
我们报告了一例继发性 T 细胞缺乏症病例,患者在接种 COVID-19 疫苗后出现慢性自发性荨麻疹,尤其是 CD4 T 细胞。在最初的一线治疗无效后,患者使用奥马珠单抗部分控制了病情。
Case report of secondary T-cell deficiency following the AstraZeneca COVID-19 vaccine
We present a case of secondary T-cell deficiency particularly affecting CD4 T cells, along with the emergence of chronic spontaneous urticaria in a patient following COVID-19 vaccination. The condition was partially managed with omalizumab after initial first-line therapy proved ineffective.