Impact of mild hypoxia on pilots’ performance and physiological response: A systematic review and experimental study

Mild hypoxia in aviation is a well-known phenomenon that affects flight safety, particularly in general aviation. Experimental research on its influence on performance and physiological response has been limited, often yielding contradictory results. This study aimed to deepen the understanding of mild hypoxia's effects on pilots' physiological responses and performance. A systematic review was conducted to synthesize existing knowledge and assess the consistency and generalizability of previous findings. Novel empirical data were then obtained through an experiment designed to focus on cardiac activity and performance under mild hypoxic conditions. Twelve male active military pilots participated in the experiment, which involved two simulated flights under controlled conditions. Unlike previous studies, which have varied significantly in methodology and outcomes, this study employed an approach to isolate the effects of mild hypoxia while simultaneously approximating real flight conditions by using a full flight simulator and a reduced oxygen breathing device. The experiment did not indicate significant performance degradation, while compensatory mechanisms in cardiac activity were observed, specifically in the form of increased heart rate and heart rate variability. These findings contribute to the existing body of knowledge by providing a more consistent methodological framework and highlighting the physiological adaptations to mild hypoxia, serving as a foundation for further investigation into the relationship between mild hypoxia, pilot performance, and physiological response.