镁参与社会行为和某些心理疾病的治疗。综述

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引用次数: 0

摘要

背景社会行为一般被定义为影响同类或受同类影响的所有行为。这种行为对于社会生活和社会进化至关重要。影响这种行为的因素有很多。镁(Mg)和大脑中的其他二价阳离子是对社会行为非常重要的因素之一,并能调节产生社会行为的许多神经机制。记忆障碍、认知、各种形式的成瘾都是重要的精神疾病,但它们对社会行为也有很大影响。镁参与社会行为的主要机制有:调节某些脑神经递质的突触前释放、突触神经可塑性、改变某些神经元受体对其激动剂的亲和力、刺激受体后的生物信号转导、某些神经元酶的活性。镁能降低种内和种间攻击性,改善记忆力和饮食行为,降低成瘾的强度和易成瘾人群的脆弱性,改善儿童的注意力缺陷,减少焦虑。镁水平的正常化可以改善许多社会行为因素。预防和纠正镁缺乏症可以降低患抑郁症、成瘾、记忆障碍、焦虑症等严重疾病的风险。将镁与治疗这些疾病的药物结合起来会有好处。
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Magnesium involvement in social behavior and in the treatment of some psychological disorders. A review

Background

Social behavior is generally defined as all behavior that influences, or is influenced by, other members of the same species. This behavior is essential for social life and the evolution of society. Numerous factors influence this behavior. One of the factors that are important for social behavior and that modulates many of the neural mechanisms involved in the production of social behavior is formed by magnesium (Mg) and other bivalent cations in the brain.

Methods

In this review, the results of some articles included in the international databases were used.

Results

Mg has an essential modulating role for a large part of the elements that are part of social behavior such as: aggression, memory and cognition, eating behavior, addictions and others. Memory disorders, cognition, all forms of addiction are important psychiatric diseases, but they also have a strong impact on social behavior. The main mechanisms by which Mg is involved in social behavior are: the modulation of the presynaptic release of some brain neurotransmitters, synaptic neuroplasticity, the modification of the affinity of some neuronal receptors for their agonists, the transduction of the biological signal after stimulating the receptors, the activity of some neuronal enzymes. Magnesium decreases intraspecific and interspecific aggression, improves memory and eating behavior, reduces the intensity of addictions and the vulnerability of people at risk of becoming addicted, improves attention deficit in children and reduces anxiety.

Conclusions

Correcting the high frequency of chronic Mg deficiency in today's society is strictly necessary and must be done as soon as possible. This normalization of the Mg level improves many of the elements of social behavior. Prevention and correction of Mg deficiency reduce the risk of developing serious diseases such as depression, addictions,memory disordres, anxiety states and other. The association of Mg with the drugs used to treat these diseases can be beneficial.
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来源期刊
Journal of trace elements and minerals
Journal of trace elements and minerals Medicine and Dentistry (General), Analytical Chemistry, Environmental Science (General), Toxicology, Biochemistry, Genetics and Molecular Biology (General), Nutrition, Veterinary Science and Veterinary Medicine (General)
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