Hangyu Luo, Xiaofeng Liu, Zhenbang Meng, Han Wang, Qi He, Ri Chen and Wenxia Wang*,
{"title":"具有伤口愈合抗菌活性的 Fe3O4/BiOI/Ag 空心微电机","authors":"Hangyu Luo, Xiaofeng Liu, Zhenbang Meng, Han Wang, Qi He, Ri Chen and Wenxia Wang*, ","doi":"10.1021/acsanm.4c0430410.1021/acsanm.4c04304","DOIUrl":null,"url":null,"abstract":"<p >Antibacterial micromotors with intriguing properties have represented frontiers of research in the biomedical and environmental fields. While single-powered micromotors still encounter some challenges for efficient propulsion in an intricate biological environment, herein, dual-propelled Fe<sub>3</sub>O<sub>4</sub>/BiOI/Ag (FBA) micromotors with hollow structure were synthesized <i>via</i> two facile steps without involving any sophisticated equipment. In this unique design, efficient propulsion of an FBA micromotor powered by magnetic stimuli/visible light was demonstrated. Impressively, the micromotor was capable of flexible propulsion with a remarkable velocity of 119.2 ± 5.9 μm s<sup>–1</sup> without addition of toxic fuel. Taking advantage of the locomotion, bacterial capture ability, and photocatalytic capacity, 1 × 10<sup>7</sup> CFU mL<sup>–1</sup> <i>Escherichia coli</i> (E. coli) can be totally inactivated by hollow FBA micromotors. The ideal universality of FBA for antibacterial application toward <i>Staphylococcus aureus</i> (S. aureus) and <i>Pseudomonas aeruginosa</i> (P. aeruginosa) was confirmed. Besides, the FBA micromotors manifested antibiofilm capacity toward <i>E. coli</i>, methicillin-resistant <i>S. aureus</i> (MRSA), and <i>P. aeruginosa</i>. It is worth mentioning that they also displayed ideal biocompatibility and lower toxicity. More importantly, the FBA micromotors can effectively accelerate <i>S. aureus</i>-infected wound healing without causing adverse effects. This work offers an innovative strategy for facile design of dual-propelled micromotors for various environmental and biomedical applications.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":null,"pages":null},"PeriodicalIF":5.3000,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Fe3O4/BiOI/Ag Hollow Micromotors with Antibacterial Activity for Wound Healing\",\"authors\":\"Hangyu Luo, Xiaofeng Liu, Zhenbang Meng, Han Wang, Qi He, Ri Chen and Wenxia Wang*, \",\"doi\":\"10.1021/acsanm.4c0430410.1021/acsanm.4c04304\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p >Antibacterial micromotors with intriguing properties have represented frontiers of research in the biomedical and environmental fields. While single-powered micromotors still encounter some challenges for efficient propulsion in an intricate biological environment, herein, dual-propelled Fe<sub>3</sub>O<sub>4</sub>/BiOI/Ag (FBA) micromotors with hollow structure were synthesized <i>via</i> two facile steps without involving any sophisticated equipment. In this unique design, efficient propulsion of an FBA micromotor powered by magnetic stimuli/visible light was demonstrated. Impressively, the micromotor was capable of flexible propulsion with a remarkable velocity of 119.2 ± 5.9 μm s<sup>–1</sup> without addition of toxic fuel. Taking advantage of the locomotion, bacterial capture ability, and photocatalytic capacity, 1 × 10<sup>7</sup> CFU mL<sup>–1</sup> <i>Escherichia coli</i> (E. coli) can be totally inactivated by hollow FBA micromotors. The ideal universality of FBA for antibacterial application toward <i>Staphylococcus aureus</i> (S. aureus) and <i>Pseudomonas aeruginosa</i> (P. aeruginosa) was confirmed. Besides, the FBA micromotors manifested antibiofilm capacity toward <i>E. coli</i>, methicillin-resistant <i>S. aureus</i> (MRSA), and <i>P. aeruginosa</i>. It is worth mentioning that they also displayed ideal biocompatibility and lower toxicity. More importantly, the FBA micromotors can effectively accelerate <i>S. aureus</i>-infected wound healing without causing adverse effects. This work offers an innovative strategy for facile design of dual-propelled micromotors for various environmental and biomedical applications.</p>\",\"PeriodicalId\":6,\"journal\":{\"name\":\"ACS Applied Nano Materials\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":5.3000,\"publicationDate\":\"2024-09-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"ACS Applied Nano Materials\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://pubs.acs.org/doi/10.1021/acsanm.4c04304\",\"RegionNum\":2,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MATERIALS SCIENCE, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Applied Nano Materials","FirstCategoryId":"88","ListUrlMain":"https://pubs.acs.org/doi/10.1021/acsanm.4c04304","RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
Fe3O4/BiOI/Ag Hollow Micromotors with Antibacterial Activity for Wound Healing
Antibacterial micromotors with intriguing properties have represented frontiers of research in the biomedical and environmental fields. While single-powered micromotors still encounter some challenges for efficient propulsion in an intricate biological environment, herein, dual-propelled Fe3O4/BiOI/Ag (FBA) micromotors with hollow structure were synthesized via two facile steps without involving any sophisticated equipment. In this unique design, efficient propulsion of an FBA micromotor powered by magnetic stimuli/visible light was demonstrated. Impressively, the micromotor was capable of flexible propulsion with a remarkable velocity of 119.2 ± 5.9 μm s–1 without addition of toxic fuel. Taking advantage of the locomotion, bacterial capture ability, and photocatalytic capacity, 1 × 107 CFU mL–1Escherichia coli (E. coli) can be totally inactivated by hollow FBA micromotors. The ideal universality of FBA for antibacterial application toward Staphylococcus aureus (S. aureus) and Pseudomonas aeruginosa (P. aeruginosa) was confirmed. Besides, the FBA micromotors manifested antibiofilm capacity toward E. coli, methicillin-resistant S. aureus (MRSA), and P. aeruginosa. It is worth mentioning that they also displayed ideal biocompatibility and lower toxicity. More importantly, the FBA micromotors can effectively accelerate S. aureus-infected wound healing without causing adverse effects. This work offers an innovative strategy for facile design of dual-propelled micromotors for various environmental and biomedical applications.
期刊介绍:
ACS Applied Nano Materials is an interdisciplinary journal publishing original research covering all aspects of engineering, chemistry, physics and biology relevant to applications of nanomaterials. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrate knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important applications of nanomaterials.