2023 年巴塞罗那基层医疗机构的抗生素使用情况,以及根据现行指南调整药盒大小可能减少的抗生素使用量。

C Llor, C Rodríguez-Bernuz, A Troncoso-Mariño
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引用次数: 0

摘要

目的:之前的研究并未对处方抗生素包装的大小进行研究。我们评估了 2023 年巴塞罗那的处方率以及药房中处方量最多的抗生素,同时还评估了如果所有阿莫西林和阿莫西林/克拉维酸钾容器都装有 20 个剂量,处方量可能会减少的情况:方法:分析了 2023 年巴塞罗那加泰罗尼亚卫生研究所初级保健医生开具的抗生素处方,计算了每千名居民和每一天的规定日剂量(DID):观察到的处方率为 8 DID,其中青霉素类占 4.6 DID(57.2%)。最常处方的抗生素是阿莫西林和阿莫西林/克拉维酸,占 4.4 DID。如果阿莫西林和阿莫西林/克拉维酸的所有 30 剂包装都是 20 剂包装,那么 DID 总数将为 3.3,从而减少 1.1 个 DID(减少 25.4%):结论:巴塞罗那的抗生素处方率较低。结论:巴塞罗那的抗生素处方率较低,按照既定指南调整抗生素剂量可进一步减少抗生素用量。
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Antibiotic use in Barcelona in 2023 in primary care and the potential reduction by adjusting box sizes to current guidelines.

Objective: Prior research has not examined the size of antibiotic packages prescribed. We assessed 2023 prescription rates in Barcelona and the most prescribed presentations in pharmacies, while evaluating potential reductions if all amoxicillin and amoxicillin/clavulanate containers had 20 doses.

Methods: Antibiotics prescribed by primary care doctors working for the Catalonian Health Institute in Barcelona in 2023 were analysed by calculating the defined daily doses per 1,000 inhabitants and day (DID).

Results: The observed prescribing rate was 8 DID, with penicillins accounting for 4.6 DID (57.2%). The most frequently prescribed antibiotics were amoxicillin and amoxicillin/clavulanate, making up 4.4 DID. If all the 30-dose presentations of amoxicillin and amoxicillin/clavulanate had been 20-dose containers, the total number of DIDs would have been 3.3, resulting in a reduction of 1.1 DID (25.4% less).

Conclusions: Antibiotic prescribing rate in Barcelona was low. Aligning the dosage of antibiotics with established guidelines could further reduce antibiotic consumption.

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