多囊卵巢综合征(PCOS)女性妊娠结局分析:回顾性研究。

IF 0.7 Q4 PHARMACOLOGY & PHARMACY Journal of pharmacy & bioallied sciences Pub Date : 2024-07-01 Epub Date: 2024-07-31 DOI:10.4103/jpbs.jpbs_233_24
Manjula Salgotra, Nancy Bharti, Varsha Sinha, Rahul Tiwari, Heena Dixit Tiwari, Chapala Shashank, Jasmine Kalsi, Priyanka R Pujari
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引用次数: 0

摘要

导言:尽管多囊卵巢综合征会影响生殖健康,但其对妊娠结果的影响仍有待讨论。将多囊卵巢综合征妇女的妊娠结局与对照组进行比较是这项回顾性研究的目标:对2017年至2022年期间来自三级医疗中心的数据进行回顾性分析。对照组(n = 300)在年龄、体重指数(BMI)和胎次方面与多囊卵巢综合征组(n = 300)相匹配,而多囊卵巢综合征组(n = 300)则符合鹿特丹标准。对母胎健康、分娩结果和妊娠问题进行了评估:与对照组相比,患有多囊卵巢综合征的妇女子痫前期(12.3% 对 8.1%,P = 0.023)和妊娠糖尿病(18.7% 对 9.8%,P < 0.001)的发病率更高。另一方面,低出生体重(P = 0.589)和早产(P = 0.321)没有明显变化:总之,多囊卵巢综合征与妊娠糖尿病和子痫前期风险增加之间的相关性强调了定制疗法的必要性。多囊卵巢综合征对分娩结果的影响错综复杂,早产和低出生体重的结果尚无定论,这就要求开展更多研究,以提高该群体母亲和新生儿的健康水平。
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Analysis of Pregnancy Outcomes in Women with Polycystic Ovary Syndrome (PCOS): A Retrospective Study.

Introduction: Although PCOS affects reproductive health, its consequences on the outcome of pregnancies are still up for discussion. Comparing the pregnancy outcomes of women with PCOS to a control group was the goal of this retrospective research.

Methods: Analysis of data from tertiary care centers between 2017 and 2022 was done in retrospective. While the controls (n = 300) matched for age, BMI, and parity, the PCOS group (n = 300) satisfied Rotterdam criteria. Maternal-fetal health, birth outcomes, and gestational problems were evaluated.

Results: Compared to controls, women with PCOS had a greater incidence of preeclampsia (12.3% vs. 8.1%, P = 0.023) and gestational diabetes (18.7% vs. 9.8%, P < 0.001). On the other hand, there were no notable variations in low birth weight (P = 0.589) or preterm delivery (P = 0.321).

Conclusion: In summary, the correlation between PCOS and increased risks of gestational diabetes and preeclampsia emphasizes the necessity of customized therapies. The intricacy of PCOS's influence on birth outcomes is shown by the inconclusive results regarding preterm delivery and low birth weight, which call for more research to enhance mother and newborn health in this group.

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