口腔健康的守护者:抗氧化剂是牙周健康的希望盟友。

IF 0.7 Q4 PHARMACOLOGY & PHARMACY Journal of pharmacy & bioallied sciences Pub Date : 2024-07-01 Epub Date: 2024-06-07 DOI:10.4103/jpbs.jpbs_440_24
Arpita Mohapatra, Akshyata Panda, Naina Pattnaik, Madhumita Mohapatra, Karandeep Singh, Anant R Sharma, Nirvi Sharma, Ramanpal S Makkad
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引用次数: 0

摘要

牙周炎是一种影响牙齿支撑结构的普遍慢性炎症,与氧化应激密切相关,其特点是活性氧生成与抗氧化防御机制之间的不平衡。由于抗氧化剂具有对抗氧化损伤和炎症的能力,因此作为牙周病治疗的潜在药物备受关注。这篇简短的综述概述了抗氧化剂在牙周炎中的作用,并重点介绍了最新的研究进展。主要内容包括抗氧化剂的作用机制、近期评估其疗效的临床前和临床研究、挑战以及基于抗氧化剂的牙周治疗的未来方向。抗氧化剂研究的最新进展为改善牙周治疗效果和患者护理提供了前景广阔的途径。
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Guardians of Oral Health: Antioxidants as Promising Allies in Periodontal Wellness.

Periodontitis, a prevalent chronic inflammatory condition affecting the supporting structures of teeth, is closely associated with oxidative stress, characterized by an imbalance between reactive oxygen species generation and antioxidant defense mechanisms. Antioxidants have garnered significant attention as potential therapeutic agents in periodontal management due to their ability to counteract oxidative damage and inflammation. This brief review provides an overview of the role of antioxidants in periodontitis, highlighting recent developments. Key topics covered include the mechanisms of action of antioxidants, recent preclinical and clinical studies evaluating their efficacy, challenges, and future directions in antioxidant-based periodontal therapy. Recent advancements in antioxidant research offer promising avenues for improving periodontal treatment outcomes and patient care.

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