针灸治疗骨质疏松症:一项多中心、随机对照临床试验。

IF 1.1 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Complementary Medicine Research Pub Date : 2024-09-26 DOI:10.1159/000541440
Yidan Chen, Huaping Qiu, Lihua Xuan, Yabei Jin, Ruixiang Chen, Shitian Teng, Xiaoqing Jin
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引用次数: 0

摘要

引言分析针灸作为早期干预治疗骨质疏松症和预防骨质疏松症的有效性:这项多中心、随机对照临床试验在 226 名骨质疏松症患者中进行,为期 6 个月。将参与者随机分为对照组(n=110)和针灸组(n=116),两组均接受每天补充碳酸钙和维生素 D3 片剂(含钙 600 毫克/片)的基本治疗(n=116),针灸组接受额外的针灸治疗,检测两组的骨矿密度(BMD)、伯格平衡量表(BBS)、骨代谢指标、下肢肌力和平衡指标,以评估两组的治疗效果:治疗6个月后,针灸组的BBS11(P=0.046)、BBS12(P=0.042)和BBS总分(P=0)均明显高于治疗前;组间比较,针灸组的BBS8在3个月和6个月后均高于对照组,差异有统计学意义(P=0.036和0.0270)。治疗 6 个月后,针灸组的 BBS 总分明显高于对照组,差异有统计学意义(P=0.039)。治疗 6 个月后,针灸组股骨颈总骨量(P=0.031)和髋关节总骨量(P=0.013)明显高于治疗前,但与对照组无统计学差异。针刺组五次坐立试验(FTSST)时间缩短,差异有统计学意义(P=0.023),但对照组无明显变化(P>0.05)。此外,针灸治疗 3 个月后,血磷(p=0.007)、β-胶原(p=0.009)和 N-骨钙素(p=0.007)的特异性序列明显低于治疗前,治疗 6 个月后血磷水平继续下降(p=0.007)。此外,针灸治疗 3 个月后,针灸组的 N-骨钙素水平明显低于对照组(P=0.008):针灸可增加骨质疏松症患者的髋关节骨密度,改善骨代谢,降低骨转换率,改善身体平衡和下肢肌肉力量。
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Acupuncture in Treating Osteopenia: A Multicenter, Randomized, Controlled Clinical Trial.

Introduction: The aim of this study was to analyze the effectiveness of acupuncture as an early intervention in the treatment of osteoporosis and prevention of osteoporosis.

Methods: This multicenter, randomized, controlled clinical trial was conducted in 226 patients with osteoporosis for 6 months. Participants were randomized to the control group (n = 110) and the acupuncture group (n = 116), both groups received basic treatment with daily calcium carbonate and vitamin D3 tablet (containing calcium 600 mg/tablet) supplementation (n = 116), and the acupuncture group received additional acupuncture treatment. Bone mineral density (BMD), Berg Balance Scale (BBS), bone metabolism indexes, and lower limb muscle strength and balance indexes were tested to evaluate the therapy outcomes of the two groups.

Results: After 6 months of treatment, BBS11 (p = 0.046), BBS12 (p = 0.042), and total BBS scores (p = 0) in the acupuncture group were significantly higher than those before treatment; comparing between groups, BBS8 in the acupuncture group was higher than that in the control group after 3 and 6 months, with statistically significant differences (p = 0.036 and 0.0270). After 6 months of treatment, the total BBS score of the acupuncture group was significantly higher than that of the control group, and the difference was statistically significant (p = 0.039). After 6 months of treatment, the BMD of total bone of femoral neck (p = 0.031) and hip joint (p = 0.013) in the acupuncture group was significantly higher than that before treatment, but there was no statistical difference with the control group. The time of five sit-to-stand test (FTSST) was shortened in the acupuncture group, and the difference was statistically significant (p = 0.023), but there was no significant change in the control group (p > 0.05). In addition, the specific sequences of blood phosphorus (p = 0.007), β-collagen (p = 0.009), and N-osteocalcin (p = 0.007) were significantly lower than before treatment after 3 months of acupuncture treatment, and the blood phosphorus level continued to decrease after 6 months of treatment (p = 0.007). In addition, the levels of N-osteocalcin in the acupuncture group were significantly lower than those in the control group after 3 months of treatment (p = 0.008).

Conclusion: Acupuncture can increase hip bone density, improve bone metabolism, reduce bone turnover rate, and improve body balance and lower limb muscle strength in patients with osteoporosis.

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来源期刊
Complementary Medicine Research
Complementary Medicine Research Medicine-Complementary and Alternative Medicine
CiteScore
2.90
自引率
5.60%
发文量
50
期刊介绍: Aims and Scope ''Complementary Medicine Research'' is an international journal that aims to bridge the gap between conventional medicine and complementary/alternative medicine (CAM) on a sound scientific basis, promoting their mutual integration. Accordingly, experts of both conventional medicine and CAM medicine cooperate on the journal‘s editorial board, which accepts papers only after a rigorous peer-review process in order to maintain a high standard of scientific quality. Spectrum of ''Complementary Medicine Research'': - Review and Original Articles, Case Reports and Essays regarding complementary practice and methods - Journal Club: Analysis and discussion of internationally published articles in complementary medicine - Editorials of leading experts in complementary medicine - Questions of complementary patient-centered care - Education in complementary medicine - Reports on important meetings and conferences - Society Bulletins of Schweizerische Medizinische Gesellschaft für Phytotherapie (SMGP) and Deutsche Gesellschaft für Naturheilkunde Bibliographic Details Complementary Medicine Research Journal Abbreviation: Complement Med Res ISSN: 2504-2092 (Print) e-ISSN: 2504-2106 (Online) DOI: 10.1159/issn.2504-2092 www.karger.com/CMR
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