金黄色葡萄球菌菌血症伴急性横贯性脊髓炎病例报告:分子技术的实用性。

IF 1.9 4区 医学 Q3 INFECTIOUS DISEASES Journal of Infection and Chemotherapy Pub Date : 2024-09-26 DOI:10.1016/j.jiac.2024.09.019
I Reffo, S Venturini, D Rufolo, M Avolio, M Domini, M T Bortolin, M Miorin, S Grosso, G Del Fabro, I Bramuzzo, A Callegari, M Crapis, G Basaglia, G Nadalin
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引用次数: 0

摘要

我们报告了一例罕见的菌血症并发急性横贯性脊髓炎(ATM)的病例,该病例因高热、四肢瘫痪和呼吸衰竭入院,病因是金黄色葡萄球菌,但无原发感染灶或继发局部感染的证据。细菌性脊髓炎(ATM)是一种罕见的临床病例,临床表现混乱,诊断困难;脊髓孤立性细菌感染,无继发性局部病灶或毗连病灶,以及金黄色葡萄球菌作为感染病因,均极为罕见。在本病例中,通过临床医生、传染病专家和临床微生物学家之间的密切合作,并在传入结果的指导下对 CSF 进行扩展分子检测,使病原学诊断得以迅速做出。
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S. aureus bacteremia with acute transverse myelitis case report: Utility of molecular techniques.

We report a rare case of bacteremia with concomitant acute transverse myelitis (ATM) without evidence of a primary infectious focus or secondary localization due to Staphylococcus aureus in a 60-year-old man admitted for hyperpyrexia, quadriplegia, and respiratory failure. Bacterial ATM is a rare clinical entity with confusing clinical presentation and challenging diagnosis; isolated bacterial infections of the spinal cord without secondary localization or contiguous foci are exceptionally rare, as is S. aureus as the cause of infection. In this case, a rapid etiologic diagnosis was made possible by close collaboration between clinicians, infectious disease specialists and clinical microbiologists combined with extended molecular testing on CSF guided by incoming results.

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来源期刊
Journal of Infection and Chemotherapy
Journal of Infection and Chemotherapy INFECTIOUS DISEASES-PHARMACOLOGY & PHARMACY
CiteScore
4.10
自引率
4.50%
发文量
303
审稿时长
47 days
期刊介绍: The Journal of Infection and Chemotherapy (JIC) — official journal of the Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases — welcomes original papers, laboratory or clinical, as well as case reports, notes, committee reports, surveillance and guidelines from all parts of the world on all aspects of chemotherapy, covering the pathogenesis, diagnosis, treatment, and control of infection, including treatment with anticancer drugs. Experimental studies on animal models and pharmacokinetics, and reports on epidemiology and clinical trials are particularly welcome.
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