术前估计 Draf III 预期直径对手术结果的影响。

IF 3 3区 医学 Q2 HEALTH CARE SCIENCES & SERVICES Journal of Personalized Medicine Pub Date : 2024-09-09 DOI:10.3390/jpm14090951
Matteo Alicandri-Ciufelli, Carla Cantaffa, Margherita Basso, Vito Colacurcio, Daniele Marchioni, Daniela Lucidi
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引用次数: 0

摘要

简介DRAF III 手术适用于治疗良性和部分恶性额窦病变。人们曾多次尝试寻找一种术中或术前测量方法,以预测该手术的可行性和成功率。其中,额窦流出道前胸直径(FOAP)似乎是最适用于临床实践的,因为它很容易在术前 CT 扫描中测量。本研究的目的是评估额窦流出道前后径的最小值和最大值(FOAP 最小值和 FOAP 最大值)是否与手术失败的风险以及手术翻修的必要性有关。其次,我们应该评估矢状面上睑板与鼻翼之间的角度是否会影响手术结果。材料和方法:这是一项回顾性研究,研究对象是 2000 年 1 月至 2022 年 7 月期间在意大利一家三级转诊中心接受 DRAF III 治疗的良性病变患者。在术前 CT 扫描的中矢状切面上测量了 FOAP 最小值和 FOAP 最大值。在同一矢状切面上还计算了唇鼻角(G-N 角)。将这些测量结果在复发和未复发的患者之间进行比较。如果有术后 CT 扫描结果,还将在同一切面上测量额窦新骨膜的前胸直径 (OD)。对术前的三个放射学参数和 OD 进行了相关性分析。结果研究共纳入 29 名患者。六名患者出现了再狭窄,需要进行手术翻修。未复发患者的中位 FOAP 最大值(中位:14.8 毫米,IQR:3.84)明显高于复发患者(中位:11.9 毫米,IQR:1.14)(p = 0.04)。FOAP 最大值与外径也呈良好的正相关(p = 0.0001;r = 0.7)。FOAP 最小值与外径之间的相关性无统计学意义,FOAP 最小值与复发风险之间也无相关性。在复发和未复发的患者中,G-N 角没有明显差异,也没有显示出与 OD 的相关性。讨论:FOAP 最大值可能是指导外科医生进行 DRAF III 手术的有效术前放射学参数,因为它易于测量,与外径有很好的相关性,而且似乎会影响复发风险。
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Influence of Pre-Operative Estimation of Draf III Expected Diameter on Surgical Outcome.

Introduction: The DRAF III procedure is indicated for the treatment of benign and selected malignant frontal sinus pathology. Several attempts have been made to find an intra or pre-operative measurement that was predictive of the feasibility of this operation and its success. Among those, the frontal sinus outflow tract anteroposterior diameter (FOAP) appears to be the one with the highest applicability in clinical practice, since it is easy to measure on pre-operative CT scan. The objective of the study is to evaluate whether the minimum and maximum frontal sinus outflow anteroposterior diameters (FOAP min and FOAP max) are associated with the risk of failure and consequently with the need for surgical revision. Secondly, we ought to evaluate whether the angle between the glabella and the nasion on the sagittal plane could influence surgical outcome. Material and Methods: This is a retrospective study on patients who underwent DRAF III for benign pathologies at a tertiary Italian referral center from January 2000 to July 2022. FOAP min and FOAP max were measured on the mid-sagittal sections of a pre-operative CT scan. The glabella-nasion angle (G-N angle) was calculated on the same sagittal section. These measurements were compared between patients who experienced a recurrence and those who did not. If a post-operative CT scan was available, the obtained anteroposterior diameter (OD) of the frontal sinus neo-ostium was also measured on the same section. A correlation analysis was performed between the three pre-operative radiologic parameters and OD. Results: Twenty-nine patients were included in the study. Six patients experienced restenosis requiring surgical revision. The median FOAP max resulted significantly higher in patients who did not experience recurrence (median: 14.8 mm, IQR: 3.84) than in patients who experienced a recurrence (median: 11.9 mm, IQR: 1.14) (p = 0.04). The FOAP max also showed a good positive correlation with OD (p = 0.0001; r = 0.7). The correlation between FOAP min and OD was not statistically significant, nor was a correlation found between FOAP min and recurrence risk. The G-N angle was not significantly different in patients who experienced recurrence and those who did not, nor did it show a correlation with OD. Discussion: The FOAP max might be a valid pre-operative radiologic parameter to guide a surgeon's approach to a DRAF III procedure, as it is easy to measure, shows a good correlation with OD, and seems to influence the risk of recurrence.

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来源期刊
Journal of Personalized Medicine
Journal of Personalized Medicine Medicine-Medicine (miscellaneous)
CiteScore
4.10
自引率
0.00%
发文量
1878
审稿时长
11 weeks
期刊介绍: Journal of Personalized Medicine (JPM; ISSN 2075-4426) is an international, open access journal aimed at bringing all aspects of personalized medicine to one platform. JPM publishes cutting edge, innovative preclinical and translational scientific research and technologies related to personalized medicine (e.g., pharmacogenomics/proteomics, systems biology). JPM recognizes that personalized medicine—the assessment of genetic, environmental and host factors that cause variability of individuals—is a challenging, transdisciplinary topic that requires discussions from a range of experts. For a comprehensive perspective of personalized medicine, JPM aims to integrate expertise from the molecular and translational sciences, therapeutics and diagnostics, as well as discussions of regulatory, social, ethical and policy aspects. We provide a forum to bring together academic and clinical researchers, biotechnology, diagnostic and pharmaceutical companies, health professionals, regulatory and ethical experts, and government and regulatory authorities.
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