猪小肠粘膜下生物材料移植用于修复小猫先天性胸膜腹膜疝。

IF 0.9 4区 农林科学 Q3 VETERINARY SCIENCES Canadian Veterinary Journal-revue Veterinaire Canadienne Pub Date : 2024-10-01
Fernando P Freitas, Katie Hoddinott
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引用次数: 0

摘要

在本病例中,使用猪小肠粘膜下层(pSIS)修补了一只小猫的巨大先天性膈疝。pSIS 在生理盐水中浸湿,对折后缝合到右侧半膈的残余部分。术后 12 周,该动物的临床表现和影像学检查均良好。8.5 月龄时,小猫绝育,检查横膈膜,发现之前 pSIS 移植的中央区域有一层半透明的薄膜。如果最初的胸部 X 光片无法明确诊断出横膈膜疝,那么连续拍摄胸部 X 光片可能是一种有效的诊断方法。外科医生应准备好使用其他技术来闭合巨大的膈肌缺损。事实证明,猪 SIS 是一种功能强大、易于使用、随时可用且有效的技术,可用于闭合膈肌的巨大缺损,并在短期和中期内取得极佳效果。在对幼年动物进行疝修补时,如果将来需要进行腹部手术(如卵巢切除术),则应考虑重新评估膈肌修补情况。在猫和狗中应考虑使用功能性 8 层 pSIS,因为它的并发症和移植物失败率较低。关键临床信息:在高度怀疑膈疝的情况下,如果连续拍片未能诊断出膈疝,则应考虑使用其他方式,如超声波或其他造影剂。应考虑使用功能性 8 层 pSIS 重建膈肌,尤其是生长中的动物,因为它是一种有效的移植物,并发症和移植物失败率都很低。
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Porcine small intestinal submucosa biomaterial graft for repair of a congenital pleuroperitoneal hernia in a kitten.

In this case, porcine small intestinal submucosa (pSIS) was used to repair a large congenital diaphragmatic hernia in a kitten. The pSIS was moistened in saline, folded in half, and sutured to the remnant of the right hemidiaphragm. The animal was determined to be doing well clinically and radiographically 12 wk after procedure. At 8.5 mo of age, the kitten was spayed, and the diaphragm was inspected, revealing a thin, semitransparent membrane at the central region of the previous pSIS graft. Serial thoracic radiographs may be an effective way to reach a diagnosis of a diaphragmatic hernia if not clearly identifiable on initial radiographs. Surgeons should be prepared to use alternative techniques to close large diaphragmatic defects. Porcine SIS was demonstrated to be a strong, easy-to-use, readily available, and effective technique to close a large defect in the diaphragm with excellent results in the short and medium terms. When hernia repair is employed in juvenile animals, reassessment of the diaphragmatic repair should be considered if future abdominal surgeries, such as ovariohysterectomies, are necessary. A functional 8-ply pSIS should be considered in cats and dogs as it has a lower complication and graft failure rate. Key clinical message: When serial radiographs fail to diagnose a diaphragmatic hernia when one is highly suspected, other modalities, such as ultrasonography or other contrast modalities, should be considered. A functional 8-ply pSIS should be considered to reconstruct the diaphragm, particularly in growing animals, as it is an effective graft with low complication and graft failure rates.

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来源期刊
CiteScore
1.20
自引率
10.00%
发文量
177
审稿时长
12-24 weeks
期刊介绍: The Canadian Veterinary Journal (CVJ) provides a forum for the discussion of all matters relevant to the veterinary profession. The mission of the Journal is to educate by informing readers of progress in clinical veterinary medicine, clinical veterinary research, and related fields of endeavor. The key objective of The CVJ is to promote the art and science of veterinary medicine and the betterment of animal health. A report suggesting that animals have been unnecessarily subjected to adverse, stressful, or harsh conditions or treatments will not be processed for publication. Experimental studies using animals will only be considered for publication if the studies have been approved by an institutional animal care committee, or equivalent, and the guidelines of the Canadian Council on Animal Care, or equivalent, have been followed by the author(s).
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