{"title":"使用瑞舒伐他汀与三氧化二铝矿物混合物对年轻的成熟恒磨牙进行直接牙髓覆盖后牙本质修复形成的放射学评估--90 天随访：一项分口研究。","authors":"Abhinandan Patra, Sonal Gupta, Asmita Das, Rohan Shrivastava","doi":"10.5005/jp-journals-10005-2844","DOIUrl":null,"url":null,"abstract":"<p><p>Direct pulp capping (DPC) includes covering the exposed pulp with a medication, dressing, or dental material to preserve its vitality. The idea behind this method of therapy is to induce the pulp to start a dentin bridge, \"walling\" the exposed site in the process. The most effective dental material to heal exposed pulp is calcium hydroxide. Mineral trioxide aggregate (MTA) causes the formation by causing cytologic and functional alterations in pulpal cells. Rosuvastatin shows pleiotropic effects like increased odontoblastic differentiation, increased mineralization, proliferation of odontoblasts, and induction of angiogenesis. Thus, the aim of the present study is to investigate pulp-dentin complex reactions following DPC with rosuvastatin vs MTA as pulp-capping materials in permanent human molars.</p><p><strong>How to cite this article: </strong>Patra A, Gupta S, Das A, <i>et al.</i> Radiographic Evaluation of Reparative Dentin Formation after Direct Pulp Capping Using Rosuvastatin vs Mineral Trioxide Aggregate on Young Mature Permanent Molar-90 Days of Follow-up: A Split-mouth Study. Int J Clin Pediatr Dent 2024;17(5):605-611.</p>","PeriodicalId":36045,"journal":{"name":"International Journal of Clinical Pediatric Dentistry","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11440674/pdf/","citationCount":"0","resultStr":"{\"title\":\"Radiographic Evaluation of Reparative Dentin Formation after Direct Pulp Capping Using Rosuvastatin vs Mineral Trioxide Aggregate on Young Mature Permanent Molar-90 Days of Follow-up: A Split-mouth Study.\",\"authors\":\"Abhinandan Patra, Sonal Gupta, Asmita Das, Rohan Shrivastava\",\"doi\":\"10.5005/jp-journals-10005-2844\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Direct pulp capping (DPC) includes covering the exposed pulp with a medication, dressing, or dental material to preserve its vitality. The idea behind this method of therapy is to induce the pulp to start a dentin bridge, \\\"walling\\\" the exposed site in the process. The most effective dental material to heal exposed pulp is calcium hydroxide. Mineral trioxide aggregate (MTA) causes the formation by causing cytologic and functional alterations in pulpal cells. Rosuvastatin shows pleiotropic effects like increased odontoblastic differentiation, increased mineralization, proliferation of odontoblasts, and induction of angiogenesis. Thus, the aim of the present study is to investigate pulp-dentin complex reactions following DPC with rosuvastatin vs MTA as pulp-capping materials in permanent human molars.</p><p><strong>How to cite this article: </strong>Patra A, Gupta S, Das A, <i>et al.</i> Radiographic Evaluation of Reparative Dentin Formation after Direct Pulp Capping Using Rosuvastatin vs Mineral Trioxide Aggregate on Young Mature Permanent Molar-90 Days of Follow-up: A Split-mouth Study. Int J Clin Pediatr Dent 2024;17(5):605-611.</p>\",\"PeriodicalId\":36045,\"journal\":{\"name\":\"International Journal of Clinical Pediatric Dentistry\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11440674/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Clinical Pediatric Dentistry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5005/jp-journals-10005-2844\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Dentistry\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Clinical Pediatric Dentistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5005/jp-journals-10005-2844","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Dentistry","Score":null,"Total":0}
引用次数: 0
摘要
直接覆盖牙髓（DPC）包括用药物、敷料或牙科材料覆盖暴露的牙髓，以保持其活力。这种治疗方法的原理是诱导牙髓开始形成牙本质桥，在此过程中 "覆盖 "暴露部位。治疗暴露牙髓最有效的牙科材料是氢氧化钙。三氧化矿物质聚合体（MTA）通过引起牙髓细胞的细胞学和功能性改变而形成。瑞舒伐他汀具有多种效应，如增加牙本质分化、增加矿化、牙本质细胞增殖和诱导血管生成。因此，本研究的目的是调查在人类恒磨牙中使用罗伐他汀与MTA作为牙髓覆盖材料进行DPC后牙髓-牙本质复合体的反应：Patra A, Gupta S, Das A, et al. Radiographic Evaluation of Reparative Dentin Formation after Direct Pulp Capping Using Rosuvastatin vs Mineral Trioxide Aggregate on Young Mature Permanent Molar-90 Days of Follow-up: A Split-mouth Study.Int J Clin Pediatr Dent 2024;17(5):605-611.
Radiographic Evaluation of Reparative Dentin Formation after Direct Pulp Capping Using Rosuvastatin vs Mineral Trioxide Aggregate on Young Mature Permanent Molar-90 Days of Follow-up: A Split-mouth Study.
Direct pulp capping (DPC) includes covering the exposed pulp with a medication, dressing, or dental material to preserve its vitality. The idea behind this method of therapy is to induce the pulp to start a dentin bridge, "walling" the exposed site in the process. The most effective dental material to heal exposed pulp is calcium hydroxide. Mineral trioxide aggregate (MTA) causes the formation by causing cytologic and functional alterations in pulpal cells. Rosuvastatin shows pleiotropic effects like increased odontoblastic differentiation, increased mineralization, proliferation of odontoblasts, and induction of angiogenesis. Thus, the aim of the present study is to investigate pulp-dentin complex reactions following DPC with rosuvastatin vs MTA as pulp-capping materials in permanent human molars.
How to cite this article: Patra A, Gupta S, Das A, et al. Radiographic Evaluation of Reparative Dentin Formation after Direct Pulp Capping Using Rosuvastatin vs Mineral Trioxide Aggregate on Young Mature Permanent Molar-90 Days of Follow-up: A Split-mouth Study. Int J Clin Pediatr Dent 2024;17(5):605-611.
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