炎症性肠病相关脊柱关节炎的诊断与治疗。

IF 8 1区 医学 Q1 GASTROENTEROLOGY & HEPATOLOGY American Journal of Gastroenterology Pub Date : 2025-01-01 Epub Date: 2024-09-23 DOI:10.14309/ajg.0000000000003092
Katherine Falloon, Michael Forney, M Elaine Husni, Brian Feagan, Florian Rieder
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引用次数: 0

摘要

摘要:炎症性肠病(IBD)相关性脊柱关节炎(SpA)很常见,但人们对它的了解仍然很少。在这篇综述文章中,我们旨在为这种疾病的诊断和治疗提供指导。对于 IBD 相关性外周脊柱关节炎(IBD-pSpA)的诊断,我们建议与风湿免疫科合作,结合临床症状、体格检查结果、关节影像学(如适用)以及现有的诊断标准。对于 IBD-pSpA 的治疗,我们首先建议对潜在的管腔 IBD 疾病活动进行评估和治疗。根据有限的现有文献,我们为 IBD-pSpA 患者的 IBD 先进疗法定位提供指导。对于 IBD 相关性轴性脊柱关节炎(IBD-axSpA)的诊断,我们建议转诊至风湿免疫科,根据症状、实验室数据、影像学检查结果(骶尾肌炎)和现有诊断标准进行诊断。对于轴向脊柱炎的治疗,我们建议与风湿免疫科共同管理,并酌情使用抗肿瘤坏死因子制剂或破伤风激酶抑制剂。
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Diagnosis and Management of Inflammatory Bowel Disease-Associated Spondyloarthritis.

Inflammatory bowel disease (IBD)-associated spondyloarthritis (SpA) is common but remains poorly understood. In this review article, we aimed to provide guidance regarding the diagnosis and management of this condition. For diagnosis of IBD-associated peripheral SpA (IBD-pSpA), we recommend collaboration with rheumatology for incorporation of clinical symptoms, physical examination findings, joint imaging if applicable, and available diagnostic criteria. For the management of IBD-pSpA, we first recommend assessment and treatment of underlying luminal IBD disease activity. We provide guidance regarding positioning of advanced therapies for IBD in patients with IBD-pSpA based on the limited available literature. For diagnosis of IBD-associated axial SpA, we recommend rheumatology referral to make the diagnosis based on incorporation of symptoms, laboratory data, imaging findings (sacroiliitis), and available diagnostic criteria. For the management of axial SpA, we recommend comanagement with rheumatology and use of either antitumor necrosis factor agents or Janus kinase inhibitors, when applicable.

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来源期刊
American Journal of Gastroenterology
American Journal of Gastroenterology 医学-胃肠肝病学
CiteScore
11.40
自引率
5.10%
发文量
458
审稿时长
12 months
期刊介绍: Published on behalf of the American College of Gastroenterology (ACG), The American Journal of Gastroenterology (AJG) stands as the foremost clinical journal in the fields of gastroenterology and hepatology. AJG offers practical and professional support to clinicians addressing the most prevalent gastroenterological disorders in patients.
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