一种独特的喹啉基荧光探针对亚硫酸氢盐的超快检测及其在智能手机辅助食品检测和生物成像中的应用。

IF 5.6 1区 化学 Q1 CHEMISTRY, ANALYTICAL Talanta Pub Date : 2024-10-01 DOI:10.1016/j.talanta.2024.126977
Xiaoyu Huang, Jiaxing Li, Yuetian Guo, Mingyu Tian, Xiaomei Yan, Lijun Tang, Keli Zhong
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引用次数: 0

摘要

二氧化硫(SO2)是大气中的主要污染物之一,极易被人体吸入并转化为其衍生物(HSO3-/SO32-),对人体健康和生态环境都有危害。因此,二氧化硫衍生物(HSO3-/SO32-)的检测非常重要。在这项工作中,我们制备了一种基于分子内电荷转移(ICT)机制的水溶性荧光探针 ID-QL,它对 HSO3- 具有比色和荧光双通道响应,具有超快、高选择性和高灵敏度的检测能力。ID-QL 尤其可用于定量检测真实食品样品中的 HSO3-。我们开发了一种便携式 ID-QL 检测条,并成功地将其与智能手机相结合,实现了对真实样品中 HSO3- 的便捷、低成本和便携式检测。该探针具有良好的线粒体靶向能力,可用于活细胞和斑马鱼体内亚硫酸盐的可视化监测和成像。
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Ultrafast detection of bisulfite by a unique quinolinium-based fluorescent probe and its applications in smartphone-assisted food detection and bioimaging.

Sulfur dioxide (SO2) is one of the major pollutants in the atmosphere, which is highly susceptible to inhalation by the human body and is converted into its derivatives (HSO3-/SO32-), which is hazardous to both human health and the ecological environment. Therefore the detection of SO2 derivatives (HSO3-/SO32-) is very important. In this work, we have prepared ID-QL, a water-soluble fluorescent probe based on the intramolecular charge transfer (ICT) mechanism, it exhibits colorimetric and fluorescent dual-channel response to HSO3- with ultrafast, highly selective and sensitive detection. In particular, ID-QL can be used for quantitative detection of HSO3- in real food samples. We developed a portable test strip for ID-QL and successfully combined it with smartphone to achieve convenient, low-cost and portable detection of HSO3- in real samples. The probe displays good mitochondrial targeting ability and can be used for visual monitoring and imaging of sulfites in live cells and zebrafish.

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来源期刊
Talanta
Talanta 化学-分析化学
CiteScore
12.30
自引率
4.90%
发文量
861
审稿时长
29 days
期刊介绍: Talanta provides a forum for the publication of original research papers, short communications, and critical reviews in all branches of pure and applied analytical chemistry. Papers are evaluated based on established guidelines, including the fundamental nature of the study, scientific novelty, substantial improvement or advantage over existing technology or methods, and demonstrated analytical applicability. Original research papers on fundamental studies, and on novel sensor and instrumentation developments, are encouraged. Novel or improved applications in areas such as clinical and biological chemistry, environmental analysis, geochemistry, materials science and engineering, and analytical platforms for omics development are welcome. Analytical performance of methods should be determined, including interference and matrix effects, and methods should be validated by comparison with a standard method, or analysis of a certified reference material. Simple spiking recoveries may not be sufficient. The developed method should especially comprise information on selectivity, sensitivity, detection limits, accuracy, and reliability. However, applying official validation or robustness studies to a routine method or technique does not necessarily constitute novelty. Proper statistical treatment of the data should be provided. Relevant literature should be cited, including related publications by the authors, and authors should discuss how their proposed methodology compares with previously reported methods.
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