荷兰 COVID-19 疫苗接种剂量的时空分布:贝叶斯生态建模分析。

IF 2.5 4区 医学 Q3 INFECTIOUS DISEASES Epidemiology and Infection Pub Date : 2024-10-07 DOI:10.1017/S0950268824001249
Haoyi Wang, Tugce Varol, Thomas Gültzow, Hanne M L Zimmermann, Robert A C Ruiter, Kai J Jonas
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引用次数: 0

摘要

在 COVID-19 流行的过渡时期,荷兰仍有相当一部分人从未接种过 COVID-19 疫苗。本研究采用贝叶斯时空模型来评估市级和地区级(公共卫生服务)COVID-19 疫苗接种(第一、第二和加强剂量)的相对机会。通过建立生态回归模型来考虑社会人口因素,我们的研究揭示了疫苗接种的不同时空分布。值得注意的是,位于荷兰主城区(Randstad)或其周边地区以及宗教信仰较为保守的地区的疫苗接种率低于平均水平。对公共卫生服务区域内市镇一级的分析表明存在内部异质性。此外,非西方移民比例较高的地区在各种接种剂量情况下的接种几率都较低。这些发现凸显了国家和地方制定有针对性的疫苗接种策略的必要性。尤其是在边缘化人口比例较高的地区,更多的地区性工作对于解决疫苗接种差异至关重要。这一见解为正在进行的 COVID-19 疫苗接种活动提供了参考,强调了在第二加强阶段采取有针对性的干预措施以优化健康结果的重要性,尤其是在边缘化人口比例相对较高的地区。
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Spatio-temporal distributions of COVID-19 vaccine doses uptake in the Netherlands: a Bayesian ecological modelling analysis.

In the transitioning era towards the COVID-19 endemic, there is still a sizable population that has never been vaccinated against COVID-19 in the Netherlands. This study employs Bayesian spatio-temporal modelling to assess the relative chances of COVID-19 vaccination uptake - first, second, and booster doses - both at the municipal and regional (public health services) levels. Incorporating ecological regression modelling to consider socio-demographic factors, our study unveils a diverse spatio-temporal distribution of vaccination uptake. Notably, the areas located in or around the Dutch main urban area (Randstad) and regions that are more religiously conservative exhibit a below-average likelihood of vaccination. Analysis at the municipal level within public health service regions indicates internal heterogeneity. Additionally, areas with a higher proportion of non-Western migrants consistently show lower chances of vaccination across vaccination dose scenarios. These findings highlight the need for tailored national and local vaccination strategies. Particularly, more regional efforts are essential to address vaccination disparities, especially in regions with elevated proportions of marginalized populations. This insight informs ongoing COVID-19 campaigns, emphasizing the importance of targeted interventions for optimizing health outcomes during the second booster phase, especially in regions with a relatively higher proportion of marginalized populations.

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来源期刊
Epidemiology and Infection
Epidemiology and Infection 医学-传染病学
CiteScore
4.10
自引率
2.40%
发文量
366
审稿时长
3-6 weeks
期刊介绍: Epidemiology & Infection publishes original reports and reviews on all aspects of infection in humans and animals. Particular emphasis is given to the epidemiology, prevention and control of infectious diseases. The scope covers the zoonoses, outbreaks, food hygiene, vaccine studies, statistics and the clinical, social and public-health aspects of infectious disease, as well as some tropical infections. It has become the key international periodical in which to find the latest reports on recently discovered infections and new technology. For those concerned with policy and planning for the control of infections, the papers on mathematical modelling of epidemics caused by historical, current and emergent infections are of particular value.
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