随机宇宙中的胚胎发育

IF 1.6 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY Bioelectricity Pub Date : 2024-09-16 eCollection Date: 2024-09-01 DOI:10.1089/bioe.2023.0050
Edward C Elson
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引用次数: 0

摘要

尽管单个真核细胞发育成复杂的成熟生物体的许多过程已被阐明,但一些生物学家仍然不明白,一组不变的、相互关联的过程是如何变得协调并与随机宇宙隔绝开来的。本文认为,源自生物体化学的电磁过程可以提供这种协调。具体来说,作者提出了起搏器的概念,即向整个胚胎发出周期性的、自主的电信号,其结果是在每个脉冲之后,改变或扩大转录组,使生物体的复杂性和成熟度达到新的水平。
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Embryo Development in a Stochastic Universe.

Despite the elucidation of the many processes by which a single eukaryotic cell develops into a complex mature organism, it is still puzzling to some biologists how it is that an unvarying, interconnected set of processes becomes coordinated and insulated from a stochastic universe. This article suggests that electromagnetic processes deriving from the chemistry of an organism may provide such coordination. Specifically, the author develops the pacemaker concept, the periodic, autonomous electrical signal to the entire embryo, the result of which, after each pulse, is to alter or enlarge the transcriptome to produce the next level of complexity and maturity of the organism.

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来源期刊
Bioelectricity
Bioelectricity Multiple-
CiteScore
3.40
自引率
4.30%
发文量
33
期刊最新文献
Bioelectricity Buzz. Embryo Development in a Stochastic Universe. From Gut Motility to Chronic Pain: Studies on the Mammalian Peripheral Nervous System. Membrane Physiology Symposium April 22nd-23rd, 2024, Napa California, USA. Potential Shortcomings of Genomic Database: The Case of Nav1.5 Expression in Breast Cancer.
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