美国按年龄和性别分列的连续体重指数与健康相关生活质量的关系。

IF 4.2 2区医学 Q1 ENDOCRINOLOGY & METABOLISM Obesity Pub Date : 2024-10-06 DOI:10.1002/oby.24141

Zachary J. Ward, Roxanne Dupuis, Michael W. Long, Steven L. Gortmaker

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引用次数: 0

摘要

研究目的本研究的目的是按连续体重指数估算美国不同年龄、性别和人口群体的健康相关生活质量（HRQoL）：我们使用 SF-6D（短表格六维度）数据估算了连续 BMI 的 HRQoL（总体和各领域），这些数据来自 2008 年至 2016 年重复性横截面医疗支出面板调查（MEPS）中 182,778 名 18 岁及以上受访者。我们对 BMI 自我报告偏差和 BMI 与 HRQoL 之间的潜在混杂因素进行了调整：我们发现，BMI 与 HRQoL 呈反 J 型曲线，女性的 HRQoL 值较低，女性 BMI 为 20.4 kg/m2 (95% CI: 20.32-20.48) 和男性 BMI 为 26.5 kg/m2 (95% CI: 26.45-26.55)时，健康效用最高。按体重指数（BMI）分类，体重超标导致的总体肥胖患者 HRQoL 损失为 0.0349，而 III 级肥胖患者的 HRQoL 损失则上升至 0.0724。按领域划分，疼痛是导致肥胖症患者 HRQoL 下降的最大原因（26%），其次是角色限制（22%）：结论：在不同年龄和体重指数水平的人群中，体重超标者的 HRQoL 都较低，尤其是在体重指数较高的情况下，疼痛是导致 HRQoL 下降的最大原因。这些发现凸显了促进全民健康体重的重要性，同时也要有针对性地努力防止在整个生命过程中体重极度增加。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Association of continuous BMI with health-related quality of life in the United States by age and sex

Objective

The objective of this study is to estimate health-related quality of life (HRQoL) by continuous BMI by age, sex, and demographic group in the United States.

Methods

We estimated HRQoL (overall and by domain) by continuous BMI using SF-6D (Short-Form Six-Dimension) data from 182,778 respondents ages 18 years and older from the repeated cross-sectional Medical Expenditure Panel Survey (MEPS) 2008 to 2016. We adjusted for BMI self-report bias and for potential confounding between BMI and HRQoL.

Results

We found an inverse J-shaped curve of HRQoL by BMI, with lower values for female individuals and the highest health utilities occurring at BMI of 20.4 kg/m² (95% CI: 20.32–20.48) for female individuals and 26.5 kg/m² (95% CI: 26.45–26.55) for male individuals. By BMI category, excess weight contributed to HRQoL loss of 0.0349 for obesity overall, rising to 0.0724 for class III obesity. By domain, pain was the largest cause of HRQoL loss for obesity (26%), followed by role limitations (22%).

Conclusions

HRQoL is lower for people with excess body weight across a broad range of ages and BMI levels, especially at high levels of BMI, with pain being the largest driver of HRQoL loss. These findings highlight the importance of promoting a healthy weight for the entire population while also targeting efforts to prevent extreme weight gain over the life course.

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来源期刊

Obesity 医学-内分泌学与代谢

CiteScore

11.70

自引率

1.40%

发文量

261

审稿时长

2-4 weeks

期刊介绍： Obesity is the official journal of The Obesity Society and is the premier source of information for increasing knowledge, fostering translational research from basic to population science, and promoting better treatment for people with obesity. Obesity publishes important peer-reviewed research and cutting-edge reviews, commentaries, and public health and medical developments.