为什么有些抑郁症患者有自杀意念,而有些却没有?从情感神经科学的角度看自杀意念 人格特质。

IF 2.6 3区 心理学 Q2 BEHAVIORAL SCIENCES Brain and Behavior Pub Date : 2024-10-08 DOI:10.1002/brb3.70077
Yasemin Hoşgören Alici, Selvi Ceran, Jamal Hasanli, Gonca Asut, Beren Özel, Zehra Ucar Hasanli, Gökçe Saygi, Arda Bağcaz, Emre Misir
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引用次数: 0

摘要

简介:虽然重度抑郁症是最常与自杀行为相关的疾病,但重度抑郁症患者是否会产生自杀意念尚不清楚。基本情感系统理论可能会为这一领域提供新颖有益的观点。本研究旨在调查基本情感系统与抑郁症患者自杀意念的关系:研究对象包括 160 名被正式诊断为重度抑郁障碍的参与者。根据参与者是否有自杀倾向(有自杀倾向的抑郁症[DS])(93 人)或无自杀倾向(无自杀倾向的抑郁症[DNS])(67 人)分为两组。研究采用了贝克抑郁量表(BDI)、自杀可能性量表(SPS)、贝克无望量表(BHS)和情感神经科学人格量表(ANPS)。数据分析采用了统计产品与服务解决方案(SPSS)24 和 SPSS 宏程序,后者是专门为评估包括序列中介在内的复杂模型而开发的:所有参与者的平均年龄为(31.1 ± 11)岁,大多数为女性(65%)。DS组有较高的精神病药物使用和自杀企图的家族史。此外,DS 组的 BDI、BHS 和 SPS 总分更高,ANGER 分量表得分也更高。在中介分析中,ANGER 子量表可显著预测是否存在自杀意念。我们观察到ANGER子量表得分对自杀意念的直接影响,以及ANGER子量表得分通过抑郁严重程度对自杀意念的间接影响:结论:ANGER得分越高,自杀意念越强。包括ANGER系统在内的神经生物学相关因素可能有助于理解自杀行为。
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Why Do Some Depressive Patients Have Suicidal Ideation but Others Not? Suicidal Ideation From the Perspective of Affective Neuroscience Personality Traits

Introduction

Although major depression is the disorder most frequently associated with suicidal behavior, it is unclear that major depressive disorder patients may develop suicidal ideation. Basic affective system theory may provide a novel and beneficial viewpoint in this field. The goal of this study was to investigate the basic affective system in relation to suicidal ideation in individuals with depression.

Method

The study population comprised 160 participants who had been formally diagnosed with major depressive disorder. Participants were divided into two groups according to whether they had suicide ideation (depression with suicide [DS]) (N = 93) or not (depression with no suicidal ideation [DNS]) (N = 67). The Beck Depression Inventory (BDI), the Suicide Probability Scale (SPS), the Beck Hopelessness Scale (BHS), and the Affective Neuroscience Personality Scale (ANPS) were applied. Statistical Product and Service Solutions (SPSS) 24 and the SPSS macroprocess, which were specifically developed for assessing complex models including serial mediators, were used to analyze the data.

Results

The mean age of all participants was 31.1 ± 11 years, and most of them were female (65%). The DS group had a higher family history of psychiatric medication use and suicidal attempts. In addition, BDI, BHS, and SPS total scores were higher, as well as ANGER subscale scores were higher in the DS group. In mediation analysis, the ANGER subscale significantly predicted the presence of suicide ideation. We observed a direct effect of the ANGER subscale score on suicide ideation as well as an indirect effect of the ANGER subscale score on suicidal ideation via depression severity.

Conclusion

Higher scores on ANGER are associated with suicidal ideation. Neurobiological correlates, including the ANGER system, may be promising in understanding suicidal behaviors.

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来源期刊
Brain and Behavior
Brain and Behavior BEHAVIORAL SCIENCES-NEUROSCIENCES
CiteScore
5.30
自引率
0.00%
发文量
352
审稿时长
14 weeks
期刊介绍: Brain and Behavior is supported by other journals published by Wiley, including a number of society-owned journals. The journals listed below support Brain and Behavior and participate in the Manuscript Transfer Program by referring articles of suitable quality and offering authors the option to have their paper, with any peer review reports, automatically transferred to Brain and Behavior. * [Acta Psychiatrica Scandinavica](https://publons.com/journal/1366/acta-psychiatrica-scandinavica) * [Addiction Biology](https://publons.com/journal/1523/addiction-biology) * [Aggressive Behavior](https://publons.com/journal/3611/aggressive-behavior) * [Brain Pathology](https://publons.com/journal/1787/brain-pathology) * [Child: Care, Health and Development](https://publons.com/journal/6111/child-care-health-and-development) * [Criminal Behaviour and Mental Health](https://publons.com/journal/3839/criminal-behaviour-and-mental-health) * [Depression and Anxiety](https://publons.com/journal/1528/depression-and-anxiety) * Developmental Neurobiology * [Developmental Science](https://publons.com/journal/1069/developmental-science) * [European Journal of Neuroscience](https://publons.com/journal/1441/european-journal-of-neuroscience) * [Genes, Brain and Behavior](https://publons.com/journal/1635/genes-brain-and-behavior) * [GLIA](https://publons.com/journal/1287/glia) * [Hippocampus](https://publons.com/journal/1056/hippocampus) * [Human Brain Mapping](https://publons.com/journal/500/human-brain-mapping) * [Journal for the Theory of Social Behaviour](https://publons.com/journal/7330/journal-for-the-theory-of-social-behaviour) * [Journal of Comparative Neurology](https://publons.com/journal/1306/journal-of-comparative-neurology) * [Journal of Neuroimaging](https://publons.com/journal/6379/journal-of-neuroimaging) * [Journal of Neuroscience Research](https://publons.com/journal/2778/journal-of-neuroscience-research) * [Journal of Organizational Behavior](https://publons.com/journal/1123/journal-of-organizational-behavior) * [Journal of the Peripheral Nervous System](https://publons.com/journal/3929/journal-of-the-peripheral-nervous-system) * [Muscle & Nerve](https://publons.com/journal/4448/muscle-and-nerve) * [Neural Pathology and Applied Neurobiology](https://publons.com/journal/2401/neuropathology-and-applied-neurobiology)
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