治疗支气管哮喘的长效β2-肾上腺素能受体激动剂吸入剂激活了棕色脂肪组织的 FDG 摄取。

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Clinical Nuclear Medicine Pub Date : 2025-03-01 Epub Date: 2024-10-10 DOI:10.1097/RLU.0000000000005529

Akira Nitta, Tomoya Kotani, Chio Okuyama

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摘要

摘要：我们在此报告了一例老年妇女的病例，她在夏季进行的 18 F-FDG PET 成像检查中可见棕色脂肪组织（BAT）。在这名患者身上，没有任何众所周知的诱发成人棕色脂肪组织活化的因素，包括寒冷暴露、儿茶酚胺生成肿瘤或服用β3-肾上腺素能受体激动剂。她每天吸入长效β2-肾上腺素能受体激动剂治疗支气管哮喘，这被认为是导致她BAT显像的原因。该病例表明，有必要将β2-肾上腺素能受体激动剂视为 BAT 可见的原因之一。

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FDG Uptake in Brown Adipose Tissue Activated by a Long-Acting β2-Adrenergic Receptor Agonist Inhaler Prescribed for Bronchial Asthma.

Abstract: We herein report a case of an elderly woman in whom brown adipose tissue (BAT) was visible on 18 F-FDG PET imaging performed in the summer. In this patient, none of the well-known factors that induce BAT activation in adults, including cold exposure, catecholamine-producing tumors, or β3-adrenergic receptor agonists administration, were present. Daily inhalation of a long-acting β2-adrenergic agonist for treatment of her bronchial asthma was considered the cause of her BAT visualization. This case suggests the need to consider β2-adrenergic receptor agonists as a cause of BAT visualization.

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.