DOTATATE PET/CT 上模仿神经内分泌肿瘤的灶性胰腺炎与放射学和病理学的相关性。

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Clinical Nuclear Medicine Pub Date : 2024-12-01 Epub Date: 2024-10-10 DOI:10.1097/RLU.0000000000005516

Lasya Daggumati, Samuel J Ballentine, Tyler J Fraum

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摘要

摘要：一名 54 岁的男子因左下腹疼痛就诊。CT 显示他的疼痛没有原因，但在胰腺尾部偶然发现了一个 2.0 厘米的增强病灶。磁共振成像显示，该病灶呈高增强和弥散限制性，怀疑为神经内分泌肿瘤。然而，在 EUS 引导下进行的活检仅发现良性胰腺组织。由于这种不一致，于是进行了64 Cu-DOTATATE PET/CT检查。胰腺尾部病变呈示踪剂avid，提示为分化良好的神经内分泌肿瘤。根据 PET 检查结果，患者接受了胰腺远端切除术。手术病理结果显示仅有局灶性慢性胰腺炎伴胰岛聚集，这是一种以前未在 DOTATATE PET/CT 上描述过的神经内分泌肿瘤。

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Focal Pancreatitis Mimicking Neuroendocrine Tumor on DOTATATE PET/CT With Radiology-Pathology Correlation.

Abstract: A 54-year-old man presented with left lower quadrant pain. CT showed no cause for his pain but identified an incidental 2.0-cm enhancing lesion in the pancreatic tail. On MRI, this lesion was hyperenhancing and diffusion-restricting, suspicious for a neuroendocrine tumor. However, EUS-guided biopsy yielded only benign pancreatic tissue. Due to this discordance, 64 Cu-DOTATATE PET/CT was performed. The pancreatic tail lesion was tracer-avid, suggesting a well-differentiated neuroendocrine tumor. Based on the PET findings, the patient underwent distal pancreatectomy. Surgical pathology revealed only focal chronic pancreatitis with islet aggregation, a previously undescribed mimic of neuroendocrine tumor on DOTATATE PET/CT.

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.