听力损失的干细胞疗法:澳大利亚听力学家及其患者的认识和观点。

IF 2.4 4区 医学 Q4 CELL & TISSUE ENGINEERING Regenerative medicine Pub Date : 2024-10-08 DOI:10.1080/17460751.2024.2402650
Dysiphan Iem, Georgia Carney, Megan Munsie, Bryony A Nayagam
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引用次数: 0

摘要

目的:在过去二十年中,大量实验研究探讨了向耳蜗输送干细胞以恢复听力的可行性。虽然这些研究催生了新的细胞疗法公司,但有关患者对这些新兴疗法的理解或期望的信息却很少:本研究旨在了解澳大利亚听力学家及其成年患者对干细胞疗法治疗听力损失的认识和看法:一项匿名调查显示,91%的患者和39%的听力学家不知道这些疗法正在开发中。30%的听力学家表示曾被问及治疗听力损失的干细胞疗法,但70%的听力学家没有信心回答患者的相关询问,也不知道从哪里收集信息。患者主要担心的是费用(45%)和治疗的安全性(42%)。有趣的是,58% 的患者不确定这种疗法会如何改善他们的听力,但其中 25% 的患者期望他们的听力会恢复正常:结论:为患者和临床医生编写教育材料得到了强烈支持。听力学家在为患者提供咨询方面发挥着越来越重要的作用,这反映在听力学家提供此类信息得到了绝大多数患者和临床医生的支持。
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Towards stem cell therapies for hearing loss: awareness and perspectives of Australian audiologists and their patients.

Aim: Over the last two decades, numerous experimental studies have examined the feasibility of delivering stem cells into the cochlea to restore hearing. While these studies have spawned new cell therapy companies, there is little information on what patients understand or expect from these emerging therapies.Methods: This study sought to understand the awareness and perspectives of Australian audiologists and their adult patients toward stem cell therapies for treating hearing loss.Results: An anonymous survey indicated 91% of patients and 39% of audiologists were unaware of these therapies being developed. Thirty percent of audiologists reported being asked about stem cell therapies for hearing loss, but 70% were not confident answering patient queries about this and were unsure where to gather information. Primary concerns reported by patients were cost (45%) and safety of treatment (42%). Interestingly, 58% of patients were unsure of how this therapy would improve their hearing, yet 25% of these patients expected that their hearing would return to normal.Conclusion: There was strong support for development of educational materials for both patient and clinician. The increasingly important role of audiologists in providing patient counselling was reflected in overwhelming support (from both patient and clinician) for audiologists providing such information.

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来源期刊
Regenerative medicine
Regenerative medicine 医学-工程:生物医学
CiteScore
4.20
自引率
3.70%
发文量
82
审稿时长
6-12 weeks
期刊介绍: Regenerative medicine replaces or regenerates human cells, tissue or organs, to restore or establish normal function*. Since 2006, Regenerative Medicine has been at the forefront of publishing the very best papers and reviews covering the entire regenerative medicine sector. The journal focusses on the entire spectrum of approaches to regenerative medicine, including small molecule drugs, biologics, biomaterials and tissue engineering, and cell and gene therapies – it’s all about regeneration and not a specific platform technology. The journal’s scope encompasses all aspects of the sector ranging from discovery research, through to clinical development, through to commercialization. Regenerative Medicine uniquely supports this important area of biomedical science and healthcare by providing a peer-reviewed journal totally committed to publishing the very best regenerative medicine research, clinical translation and commercialization. Regenerative Medicine provides a specialist forum to address the important challenges and advances in regenerative medicine, delivering this essential information in concise, clear and attractive article formats – vital to a rapidly growing, multidisciplinary and increasingly time-constrained community. Despite substantial developments in our knowledge and understanding of regeneration, the field is still in its infancy. However, progress is accelerating. The next few decades will see the discovery and development of transformative therapies for patients, and in some cases, even cures. Regenerative Medicine will continue to provide a critical overview of these advances as they progress, undergo clinical trials, and eventually become mainstream medicine.
期刊最新文献
Bone marrow aspirate concentrate for the treatment of fifth metatarsal head stress fracture: a case report. Proliferation and differentiation of Wharton's jelly-derived mesenchymal stem cells on prgf-treated hydrogel scaffold. ATMP clinical trials in the UK. Industry updates from the field of stem cell research and regenerative medicine in September 2024. Correction.
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