研究杏仁核和情绪的入口。

IF 2.9 2区 医学 Q2 NEUROSCIENCES Cerebral cortex Pub Date : 2024-10-11 DOI:10.1093/cercor/bhae408
Lizabeth M Romanski
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引用次数: 0

摘要

研究杏仁核及其在情绪处理中的作用已成为神经科学的一个共同焦点。这一领域的研究在现代得到了扩展,部分原因是发现了传递情绪信息的皮层下通路,以及为研究这一通路而开发的实验范式。90 年代的突破性实验利用啮齿动物模型的解剖学、神经生理学和行为损伤研究,揭示了简单情绪记忆的神经回路。这些研究利用传统工具和行为学方法证明了特定单突触通路在情绪记忆中的重要作用。动物模型与简单而适当的经典条件反射范式的开发,使情绪神经基础的实验研究成为可能,并为一代神经科学家所掌握。这些工具和对杏仁核神经连接及其在情绪记忆中的重要作用的关注,推动了有关杏仁核和情绪研究的爆炸式增长。
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Gateway to the study of the amygdala and emotion.

The study of the amygdala and its role in the processing of emotions has become a common focus in neuroscience. The modern expansion of research in this area is partly due to the discovery of a subcortical pathway for the transmission of emotional information and the experimental paradigm that was developed to study it. Groundbreaking experiments during the 90s utilized anatomical, neurophysiological, and behavioral lesion studies in a rodent animal model to uncover the neural circuitry of a simple emotional memory. These studies demonstrated the essential role of a specific monosynaptic pathway in emotional memory, using traditional tools and behavioral methods. The development of an animal model with a simple and appropriate classical conditioning paradigm made experimental investigations into the neural basis of emotion tenable and available to a generation of neuroscientists. These tools and a focus on the amygdala's neural connections and their essential role in emotional memory were a driving force in the explosion of research regarding the amygdala and emotion.

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来源期刊
Cerebral cortex
Cerebral cortex 医学-神经科学
CiteScore
6.30
自引率
8.10%
发文量
510
审稿时长
2 months
期刊介绍: Cerebral Cortex publishes papers on the development, organization, plasticity, and function of the cerebral cortex, including the hippocampus. Studies with clear relevance to the cerebral cortex, such as the thalamocortical relationship or cortico-subcortical interactions, are also included. The journal is multidisciplinary and covers the large variety of modern neurobiological and neuropsychological techniques, including anatomy, biochemistry, molecular neurobiology, electrophysiology, behavior, artificial intelligence, and theoretical modeling. In addition to research articles, special features such as brief reviews, book reviews, and commentaries are included.
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