建立自动化设备处理中心,改造科研企业配置。

IF 1.3 4区 农林科学 Q2 VETERINARY SCIENCES Laboratory Animals Pub Date : 2024-10-11 DOI:10.1177/00236772241262827
Philip J Richter, Albert LeClair, Harry Lim
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引用次数: 0

摘要

一所顶级公立大学制定了集中设备卫生和处理的战略,以应对其不断扩大的体内研究企业所面临的日益增长的物理基础设施和人力资源挑战。随后,该校建立了一个与所有动物研究设施分开的自动化设备处理中心,自 2016 年以来一直在持续运行。该设施采用了流程自动化等系统,以尽可能高效地对设备进行消毒和灭菌。对新的集中式研究企业配置与旧的分布式研究企业配置之间差异的分析表明,到目前为止,估计总财政收益近 5 400 万美元,预计到 2028 年将达到 1.24 亿美元。据估计,在新配置下,9 年的公用事业运行消耗将减少超过 1.25 亿加仑的水、1400 万加仑的冷冻水、1.21 亿磅的蒸汽和近 360 万千瓦的电力,预计到 2028 年,消耗节省将显著增加。此外,还确定了其他的运营和组织效益以及直接的研究效益。新的配置已经运行了 9 年,在研究企业内部没有发现交叉污染,从而证明设备处理地点的 "微生物 "风险因素比以前所认为的要小。
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Development of a center for automated equipment processing to transform the research enterprise configuration.

The strategy of centralizing equipment sanitation and processing was developed by a top-tier public university to address the growing physical infrastructure and human resource challenges of its expanding in-vivo research enterprise. Subsequently, a center for automated equipment processing physically separate from all animal research facilities was developed and has operated consistently since 2016. The facility incorporates systems such as process automation to sanitize and sterilize equipment as efficiently as possible. Analysis of the differences between the new centralized and old distributed research enterprise configurations shows a total estimated fiscal benefit of almost US$54 m to date projected out to US$124 m through 2028. Utility consumption of operations over nine years in the new configuration was estimated to be decreased by over 125 million gallons of water, 14 million gallons of chilled water, 121 million pounds of steam, and almost 3.6 million kilowatts of electricity, with consumption savings significantly increased projected out to 2028. Additional operational and organizational benefits as well as direct research benefits were identified. The new configuration has functioned for nine years without detectable cross contamination within the research enterprise thus providing evidence that the location of equipment processing can be less of a "microbial" risk factor than previously attributed.

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来源期刊
Laboratory Animals
Laboratory Animals 生物-动物学
CiteScore
4.90
自引率
8.30%
发文量
64
审稿时长
6-12 weeks
期刊介绍: The international journal of laboratory animal science and welfare, Laboratory Animals publishes peer-reviewed original papers and reviews on all aspects of the use of animals in biomedical research. The journal promotes improvements in the welfare or well-being of the animals used, it particularly focuses on research that reduces the number of animals used or which replaces animal models with in vitro alternatives.
期刊最新文献
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