{"title":"通过 6-exo-trig 多米诺自由基加成/环化/脱芳烃作用，以可见光诱导双芳基炔酮的双 CH 功能化：高效获得烷基化螺[5.5]三烯酮","authors":"","doi":"10.1016/j.tetlet.2024.155312","DOIUrl":null,"url":null,"abstract":"<div><div>A visible-light-induced 6-exo-trig tandem cyclization dearomatization of biaryl ynones with simple ethers was developed. The reaction involves selective C(sp<sup>3</sup>)<img>H bond cleavage and dual C<img>C bond formation providing efficient, atom and step economical access to alkylated spiro[5.5]trienones under mild conditions.</div></div>","PeriodicalId":438,"journal":{"name":"Tetrahedron Letters","volume":null,"pages":null},"PeriodicalIF":1.5000,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Visible-light-induced dual CH functionalization of biaryl ynones via a 6-exo-trig domino radical addition/cyclization/dearomatization: Efficient access to alkylated spiro[5.5] trienones\",\"authors\":\"\",\"doi\":\"10.1016/j.tetlet.2024.155312\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>A visible-light-induced 6-exo-trig tandem cyclization dearomatization of biaryl ynones with simple ethers was developed. The reaction involves selective C(sp<sup>3</sup>)<img>H bond cleavage and dual C<img>C bond formation providing efficient, atom and step economical access to alkylated spiro[5.5]trienones under mild conditions.</div></div>\",\"PeriodicalId\":438,\"journal\":{\"name\":\"Tetrahedron Letters\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2024-09-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Tetrahedron Letters\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0040403924004076\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, ORGANIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tetrahedron Letters","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0040403924004076","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
摘要
研究人员开发了一种可见光诱导的双芳基炔酮与单醚的 6-exo-trig 串联环化脱芳烃反应。该反应涉及选择性 C(sp3)H 键裂解和双 CC 键形成，可在温和条件下高效、经济地获得烷基化螺[5.5]三烯酮。
Visible-light-induced dual CH functionalization of biaryl ynones via a 6-exo-trig domino radical addition/cyclization/dearomatization: Efficient access to alkylated spiro[5.5] trienones
A visible-light-induced 6-exo-trig tandem cyclization dearomatization of biaryl ynones with simple ethers was developed. The reaction involves selective C(sp3)H bond cleavage and dual CC bond formation providing efficient, atom and step economical access to alkylated spiro[5.5]trienones under mild conditions.
期刊介绍：
Tetrahedron Letters provides maximum dissemination of outstanding developments in organic chemistry. The journal is published weekly and covers developments in techniques, structures, methods and conclusions in experimental and theoretical organic chemistry. Rapid publication of timely and significant research results enables researchers from all over the world to transmit quickly their new contributions to large, international audiences.
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