采用全食物植物性饮食后，勃起功能障碍得到逆转

IF 4.3 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS American journal of preventive cardiology Pub Date : 2024-09-01 DOI:10.1016/j.ajpc.2024.100772

Robert J Ostfeld MD, MSc

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引用次数: 0

摘要

治疗领域其他：C 先生现年 52 岁，患有心血管疾病，于 2024 年 2 月来到蒙特菲奥里医院的心脏健康计划。他患有高脂血症，从 28 岁起就开始服用他汀类药物。他没有已知的心肌梗塞、糖尿病、中风、甲状腺机能减退、性腺机能减退、心力衰竭、吸烟或非法药物使用史。自 2021 年 6 月以来，他经常锻炼身体。血压为 110/72，脉搏为 79，体重指数为 28kg/m2。从 2011 年到 2022 年 4 月，他的饮食一直很 "健康"。从周日到周五晚上，他的饮食包括沙拉、豆类、蘑菇、全谷物、汤、植物奶昔和加工过的素食零食。2022 年 4 月，他开始全食物植物性饮食（WFPB）。大约三个月后，他发现自己的勃起功能有所改善。2023 年 7 月，他听说多吃绿叶蔬菜可以增加一氧化氮的产生，于是他将每天的绿叶蔬菜份量（每份为一小把）从 3 份增加到 6 份。他的勃起功能在几个月内恢复正常。他接受了 "国际勃起功能指数-5"（International Index of Erectile Function-5）问卷调查，这是一项经过验证的勃起功能测量方法，他按照以下时间点进行了回答：1/2021：1/2021：放置支架前：9（中度ED）3/2022：开始WFPB饮食前：9（中度ED）6/2022：开始WFPB饮食前：9（中度ED9（中度 ED）6/2023：背景勃起功能障碍是冠状动脉疾病（CAD）的 "煤矿金丝雀"，因为勃起功能障碍通常比冠状动脉疾病早出现 3-5 年。据我们所知，这是首例在采用全食物链饮食后勃起功能障碍得到缓解的病例。

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ERECTILE DYSFUNCTION REVERSED AFTER ADOPTION OF A WHOLE FOOD PLANT-BASED DIET

Therapeutic Area

Other: Erectile Dysfunction

Case Presentation

Mr. C is a 52-year-old with cardiovascular disease who presented to our Cardiac Wellness Program at Montefiore on February 2024.

Since at least 2019, he reported not having morning erections and having worsening erectile function. He was not on medications associated with erectile dysfunction (ED).

In January 2021, he had a drug-eluting stent placed in his left anterior descending artery for stable angina.

He has hyperlipidemia for which he has been on statin since the age of 28. He has no known history of myocardial infarction, diabetes, stroke, hypothyroidism, hypogonadism, heart failure, smoking, or illicit drug use. He has never used medications to treat ED.

He exercised regularly since June 2021.

Blood pressure was 110/72, pulse 79, BMI 28kg/m². Physical exam was unremarkable.

He had been eating “healthfully” from 2011 until April 2022. From Sunday until Friday night his diet consisted of salads, beans, mushrooms, whole grains, soups, plant-based shakes, and processed vegan snack foods. From Friday night until Sunday he would consume “high volumes” of cheese, meats, and highly processed foods.

In April 2022, he started a whole-food plant-based diet (WFPB). About three months later, he noticed improvements in his erectile function.

In July of 2023, he heard that eating more green leafy vegetables may increase nitric oxide production, so he increased his daily servings (each serving was a handful) of greens from 3 to 6. His erectile function normalized within months.

He was given the International Index of Erectile Function-5 questionnaire, a validated measure of erectile function and answered as if he were at the following time points:

1/2021: Directly before stent placement: 9 (Moderate ED)

3/2022: Directly before beginning a WFPB diet: 9 (Moderate ED)

6/2023: Directly before beginning 6 daily servings of greens: 20 (Mild ED)

2/2024: 25 (Normal sexual function)

Background

Erectile dysfunction is the “canary in the coal mine” for coronary disease (CAD) as ED typically presents 3-5 years before CAD. Vascular ED shares the same risk factors as CAD.