Evaluation of swim bladder-derived oligopeptides on skin nutrition and health in vitro

Human fibroblast cells (BJ cells) were used in vitro to study the skin-care effects of fish swim bladder oligopeptides (FSBOP). Wound healing results showed that cell migration was significantly enhanced in cells treated with 0.5 % FSBOP (P < 0.05). SOD and GSH-Px activities in cells treated with 0.5 %, 1 % and 2 % FSBOP were significantly increased (P < 0.05). In addition, 1 % vitamin E (VE) and fish collagen peptide (CP) significantly induced SOD and GSH-Px activitiy. The hydroxyproline (HYP) content increased after treatment with FSBOP, CP, and VE (P < 0.05). The cells showed greater amounts of hyaluronic acid (HA) in the 1 % and 2 % FSBOP groups (P < 0.05). The HA content in the 1 % VE and FSBOP groups was significantly higher (P < 0.05). It was concluded that oligopeptides might be useful in the cosmetics industry as oligopeptides have good antioxidant, moisturizing, and anti-wrinkle effects, and promote wound repair.