LEAT 和其他脑肿瘤的癫痫：重点回顾

IF 2.3 3区医学 Q2 BEHAVIORAL SCIENCES Epilepsy & Behavior Pub Date : 2024-11-01 Epub Date: 2024-10-15 DOI:10.1016/j.yebeh.2024.110092

Catrin Mann , Nico Melzer , Dorothea Münch

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引用次数: 0

摘要

在所有脑肿瘤患者中，约有 30-50% 会出现癫痫发作。低级别癫痫相关脑肿瘤（LEAT）发生癫痫的概率尤其高。低级别脑肿瘤通常表现出明显的网络功能障碍，伴有广泛的脑电图病变和认知障碍，而且癫痫通常难以治疗。在高级别脑肿瘤中，癫痫发作决定了发病率和生活质量。人们对脑肿瘤癫痫发生的基本机制有了越来越多的了解，这为个性化治疗方法带来了希望。本文是一篇简短而集中的综述，概述了目前对脑肿瘤相关癫痫的认识。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Epilepsy in LEAT and other brain tumors: A focused review

Of all patients with brain tumors, about 30–50% suffer from epileptic seizures. The probability of developing epilepsy is particularly high in low-grade, epilepsy-associated brain tumors (LEAT). LEATs often show a pronounced network dysfunction with extensive EEG pathologies and cognitive deficits, and the epilepsies are often difficult to treat. In high-grade brain tumors, epileptic seizures determine morbidity and quality of life. The underlying mechanisms of epileptogenesis of brain tumors are increasingly understood and raise hope for personalized therapeutic approaches. This short, focused review provides an overview of the current understanding of brain tumor-related epilepsies.

This paper was presented at 16th International Epilepsy Course and Colloquium held in Frankfurt a.M., Germany, September 2024.

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来源期刊

Epilepsy & Behavior 医学-行为科学

CiteScore

5.40

自引率

15.40%

发文量

385

审稿时长

43 days

期刊介绍： Epilepsy & Behavior is the fastest-growing international journal uniquely devoted to the rapid dissemination of the most current information available on the behavioral aspects of seizures and epilepsy. Epilepsy & Behavior presents original peer-reviewed articles based on laboratory and clinical research. Topics are drawn from a variety of fields, including clinical neurology, neurosurgery, neuropsychiatry, neuropsychology, neurophysiology, neuropharmacology, and neuroimaging. From September 2012 Epilepsy & Behavior stopped accepting Case Reports for publication in the journal. From this date authors who submit to Epilepsy & Behavior will be offered a transfer or asked to resubmit their Case Reports to its new sister journal, Epilepsy & Behavior Case Reports.