通过亲水涂层模式调整 NaGd0.7Eu0.3F4 纳米晶体的双重对比能力

IF 1.8 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY Mendeleev Communications Pub Date : 2024-09-01 DOI:10.1016/j.mencom.2024.09.004

Alexey A. Dovzhenko , Anna A. Betina , Tatyana S. Bulatova , Nikita A. Bogachev , Vladimir G. Nikiforov , Alexandra D. Voloshina , Rustem R. Zairov , Asya R. Mustafina , Andrey S. Mereshchenko , Bulat S. Akhmadeev

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引用次数: 0

摘要

这项研究介绍了用聚赖氨酸（PL）和聚乙烯亚胺（PEI）对 NaGd0.7Eu0.3F4 纳米晶体进行非共价亲水包覆，用于核磁共振成像和荧光成像。聚赖氨酸和聚乙烯亚胺稳定的纳米晶体具有高胶体稳定性、细胞内化、细胞核和细胞质的荧光对比、低细胞毒性和弛豫性（r1= 0.17 dm3 mmol-1 s-1 和 r1 = 0.23 dm3 mmol-1 s-1）。

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Dual contrasting ability of NaGd0.7Eu0.3F4 nanocrystals tuned by their hydrophilic coating mode

This work introduces non-covalent hydrophilic coating of NaGd_0.7Eu_0.3F₄ nanocrystals by polylysine (PL) and polyethyleneimine (PEI) for MRI and fluorescent imaging purposes. PL- and PEI-stabilized nanocrystals exhibit high colloidal stability, cell internalization, fluorescent contrasting of nuclei and cytoplasm, low cytotoxicity, and relaxivity (r₁= 0.17 dm³ mmol^–1 s^–1 and r₁ = 0.23 dm³ mmol^–1 s^–1).

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来源期刊

Mendeleev Communications 化学-化学综合

CiteScore

3.00

自引率

21.10%

发文量

226

审稿时长

4-8 weeks

期刊介绍： Mendeleev Communications is the journal of the Russian Academy of Sciences, launched jointly by the Academy of Sciences of the USSR and the Royal Society of Chemistry (United Kingdom) in 1991. Starting from 1st January 2007, Elsevier is the new publishing partner of Mendeleev Communications. Mendeleev Communications publishes short communications in chemistry. The journal primarily features papers from the Russian Federation and the other states of the former USSR. However, it also includes papers by authors from other parts of the world. Mendeleev Communications is not a translated journal, but instead is published directly in English. The International Editorial Board is composed of eminent scientists who provide advice on refereeing policy.

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