K. Ferchichi , A. Chamli , R. Frioui , I. Helal , H. Hammami , A. Zaouak , S. Fenniche
{"title":"揭开悖论的面纱：英夫利昔单抗诱发寻常型银屑病中的脓疱型银屑病","authors":"K. Ferchichi , A. Chamli , R. Frioui , I. Helal , H. Hammami , A. Zaouak , S. Fenniche","doi":"10.1016/j.reval.2024.104165","DOIUrl":null,"url":null,"abstract":"<div><div>Paradoxical psoriasis induced by tumor necrosis factor-alpha (TNF-α) antagonists is a rare adverse reaction of these drugs, with the pustular presentation being even more uncommon. Diagnosing and management of paradoxical pustular psoriasis in patients undergoing TNF-α antagonists treatment for psoriasis can be challenging. Therefore, we present a case report highlighting the occurrence of paradoxical pustular psoriasis caused by infliximab in a patient undergoing infliximab treatment for psoriasis, two weeks after the ninth injection. A switch to another TNF-α antagonist was considered, with no relapses at 6-month follow-up. This case underscores the importance of vigilant monitoring and recognition of atypical reactions and considering the switch to another TNF-α antagonist as a safe option for these patients.</div></div>","PeriodicalId":49130,"journal":{"name":"Revue Francaise d Allergologie","volume":"64 6","pages":"Article 104165"},"PeriodicalIF":0.3000,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Unveiling the paradox: Infliximab-induced pustular psoriasis in psoriasis vulgaris\",\"authors\":\"K. Ferchichi , A. Chamli , R. Frioui , I. Helal , H. Hammami , A. Zaouak , S. Fenniche\",\"doi\":\"10.1016/j.reval.2024.104165\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Paradoxical psoriasis induced by tumor necrosis factor-alpha (TNF-α) antagonists is a rare adverse reaction of these drugs, with the pustular presentation being even more uncommon. Diagnosing and management of paradoxical pustular psoriasis in patients undergoing TNF-α antagonists treatment for psoriasis can be challenging. Therefore, we present a case report highlighting the occurrence of paradoxical pustular psoriasis caused by infliximab in a patient undergoing infliximab treatment for psoriasis, two weeks after the ninth injection. A switch to another TNF-α antagonist was considered, with no relapses at 6-month follow-up. This case underscores the importance of vigilant monitoring and recognition of atypical reactions and considering the switch to another TNF-α antagonist as a safe option for these patients.</div></div>\",\"PeriodicalId\":49130,\"journal\":{\"name\":\"Revue Francaise d Allergologie\",\"volume\":\"64 6\",\"pages\":\"Article 104165\"},\"PeriodicalIF\":0.3000,\"publicationDate\":\"2024-10-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revue Francaise d Allergologie\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1877032024003865\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revue Francaise d Allergologie","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1877032024003865","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Unveiling the paradox: Infliximab-induced pustular psoriasis in psoriasis vulgaris
Paradoxical psoriasis induced by tumor necrosis factor-alpha (TNF-α) antagonists is a rare adverse reaction of these drugs, with the pustular presentation being even more uncommon. Diagnosing and management of paradoxical pustular psoriasis in patients undergoing TNF-α antagonists treatment for psoriasis can be challenging. Therefore, we present a case report highlighting the occurrence of paradoxical pustular psoriasis caused by infliximab in a patient undergoing infliximab treatment for psoriasis, two weeks after the ninth injection. A switch to another TNF-α antagonist was considered, with no relapses at 6-month follow-up. This case underscores the importance of vigilant monitoring and recognition of atypical reactions and considering the switch to another TNF-α antagonist as a safe option for these patients.
期刊介绍：
La Revue Française d''Allergologie : un véritable forum pour faire connaître des travaux originaux et permettre la diffusion de l''information auprès de toutes les spécialités concernées par les pathologies allergiques. La Revue Française d''Allergologie (8 numéros par an) est au carrefour de nombreuses spécialités - dermatologie, pédiatrie, ORL, pneumologie, ophtalmologie, médecine interne - qui, toutes, ont à traiter des maladies allergiques. Les symptômes des allergies fondés sur des mécanismes communs sont le plus souvent associés et se succèdent chez un même patient. En forte progression depuis 20 ans, les maladies allergiques sont dans l''attente de perfectionnements et d''avancées thérapeutiques qui permettront aux nombreux patients qui en sont atteints de mieux vivre avec leurs allergies. La Revue Française d''Allergologie se veut donc un véritable forum de discussions et d''échanges entre tous les spécialistes confrontés aux pathologies
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