基于磁共振成像的分层可降低前列腺癌过度诊断的风险

IF 81.1 1区 医学 Q1 ONCOLOGY Nature Reviews Clinical Oncology Pub Date : 2024-10-16 DOI:10.1038/s41571-024-00957-0
Peter Sidaway
{"title":"基于磁共振成像的分层可降低前列腺癌过度诊断的风险","authors":"Peter Sidaway","doi":"10.1038/s41571-024-00957-0","DOIUrl":null,"url":null,"abstract":"","PeriodicalId":19079,"journal":{"name":"Nature Reviews Clinical Oncology","volume":"21 12","pages":"838-838"},"PeriodicalIF":81.1000,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"MRI-based stratification reduces the risk of overdiagnosis of prostate cancer\",\"authors\":\"Peter Sidaway\",\"doi\":\"10.1038/s41571-024-00957-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\",\"PeriodicalId\":19079,\"journal\":{\"name\":\"Nature Reviews Clinical Oncology\",\"volume\":\"21 12\",\"pages\":\"838-838\"},\"PeriodicalIF\":81.1000,\"publicationDate\":\"2024-10-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature Reviews Clinical Oncology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.nature.com/articles/s41571-024-00957-0\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ONCOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature Reviews Clinical Oncology","FirstCategoryId":"3","ListUrlMain":"https://www.nature.com/articles/s41571-024-00957-0","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

血清前列腺特异性抗原(PSA)达到3.0纳克/毫升的男性通常会被转诊接受进一步的前列腺癌诊断检查;然而,许多男性要么没有患病,要么患有低风险肿瘤,可能会因不必要的诊断程序和/或过度治疗而发生不良事件。在GÖTEBORG-2研究中,共有13153名50-60岁的男性根据基线结果在首次检测后的2年、4年或8年接受了血清PSA监测,任何一轮检测中血清PSA达到3.0纳克/毫升作为进一步检查的阈值。这些男性按1:1的比例随机分配接受前列腺核磁共振成像检查,然后无论核磁共振成像检查结果如何都进行系统的活检取样,而如果在核磁共振成像检查中发现可疑病变,则只进行有针对性的活检取样。临床意义不大(国际泌尿病理学会(ISUP)1级)前列腺癌的检出率是主要终点。发现临床意义重大(ISUP 等级≥2)的前列腺癌是次要终点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
MRI-based stratification reduces the risk of overdiagnosis of prostate cancer
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
99.40
自引率
0.40%
发文量
114
审稿时长
6-12 weeks
期刊介绍: Nature Reviews publishes clinical content authored by internationally renowned clinical academics and researchers, catering to readers in the medical sciences at postgraduate levels and beyond. Although targeted at practicing doctors, researchers, and academics within specific specialties, the aim is to ensure accessibility for readers across various medical disciplines. The journal features in-depth Reviews offering authoritative and current information, contextualizing topics within the history and development of a field. Perspectives, News & Views articles, and the Research Highlights section provide topical discussions, opinions, and filtered primary research from diverse medical journals.
期刊最新文献
Late-line options for patients with metastatic colorectal cancer: a review and evidence-based algorithm Allogeneic chimeric antigen receptor cell therapies for cancer: progress made and remaining roadblocks First-line triplet therapy for advanced-stage PIK3CA-mutant HR+ breast cancer improves outcomes Expanding the use of T-DXd in metastatic HR-positive breast cancer: where are we now? On the cusp of targeted therapy for cancer cachexia — what clinical benefits might we promise our patients?
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1