{"title":"KIM-1 在有创心脏手术后造影剂诱发肾病的早期诊断中的作用：系统综述","authors":"Mantasha Shuaib , Md Masoom , Mohd Ashif Khan","doi":"10.1016/j.cegh.2024.101765","DOIUrl":null,"url":null,"abstract":"<div><div>This systematic review aims to provide a comprehensive analysis of the diagnostic efficacy of KIM-1 in CI-AKI. We evaluated its potential as a robust biomarker for the early identification and prediction of AKI progression.</div></div><div><h3>Methodology</h3><div>To assess KIM-1 as a biomarker for CI-AKI, relevant databases were searched. Inclusion criteria comprised studies measuring KIM-1 levels in patients undergoing cardiac procedures with contrast media and data were extracted. Methodological quality and bias were evaluated using Quadas-2 tool.</div></div><div><h3>Conclusion</h3><div>KIM-1 shows promise as a biomarker for renal injury. Its upregulation, correlation with injury severity, and involvement in tissue repair support its clinical relevance.</div></div><div><h3>Prospero registration number</h3><div>CRD42023431419.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":null,"pages":null},"PeriodicalIF":2.3000,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Role of KIM-1 in early diagnosis of contrast-induced nephropathy following invasive cardiac procedure: A systematic review\",\"authors\":\"Mantasha Shuaib , Md Masoom , Mohd Ashif Khan\",\"doi\":\"10.1016/j.cegh.2024.101765\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>This systematic review aims to provide a comprehensive analysis of the diagnostic efficacy of KIM-1 in CI-AKI. We evaluated its potential as a robust biomarker for the early identification and prediction of AKI progression.</div></div><div><h3>Methodology</h3><div>To assess KIM-1 as a biomarker for CI-AKI, relevant databases were searched. Inclusion criteria comprised studies measuring KIM-1 levels in patients undergoing cardiac procedures with contrast media and data were extracted. Methodological quality and bias were evaluated using Quadas-2 tool.</div></div><div><h3>Conclusion</h3><div>KIM-1 shows promise as a biomarker for renal injury. Its upregulation, correlation with injury severity, and involvement in tissue repair support its clinical relevance.</div></div><div><h3>Prospero registration number</h3><div>CRD42023431419.</div></div>\",\"PeriodicalId\":46404,\"journal\":{\"name\":\"Clinical Epidemiology and Global Health\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2024-10-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Epidemiology and Global Health\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2213398424002628\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Epidemiology and Global Health","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2213398424002628","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
Role of KIM-1 in early diagnosis of contrast-induced nephropathy following invasive cardiac procedure: A systematic review
This systematic review aims to provide a comprehensive analysis of the diagnostic efficacy of KIM-1 in CI-AKI. We evaluated its potential as a robust biomarker for the early identification and prediction of AKI progression.
Methodology
To assess KIM-1 as a biomarker for CI-AKI, relevant databases were searched. Inclusion criteria comprised studies measuring KIM-1 levels in patients undergoing cardiac procedures with contrast media and data were extracted. Methodological quality and bias were evaluated using Quadas-2 tool.
Conclusion
KIM-1 shows promise as a biomarker for renal injury. Its upregulation, correlation with injury severity, and involvement in tissue repair support its clinical relevance.
期刊介绍：
Clinical Epidemiology and Global Health (CEGH) is a multidisciplinary journal and it is published four times (March, June, September, December) a year. The mandate of CEGH is to promote articles on clinical epidemiology with focus on developing countries in the context of global health. We also accept articles from other countries. It publishes original research work across all disciplines of medicine and allied sciences, related to clinical epidemiology and global health. The journal publishes Original articles, Review articles, Evidence Summaries, Letters to the Editor. All articles published in CEGH are peer-reviewed and published online for immediate access and citation.
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