{"title":"通过下一代测序鉴定出一个新的 HLA-DPA1 等位基因 HLA-DPA1*01:204","authors":"Xiong-jie He, Kun-Xiang Wang, Peng Zhang, Ti-Long Huang, Xian-Wen Zhang","doi":"10.1111/tan.15710","DOIUrl":null,"url":null,"abstract":"<div>\n \n <p><i>HLA-DPA1*01:204</i> has a single nucleotide substitution at position 426G > T when compared to the <i>HLA-DPA1*01:03:01:15</i> allele.</p>\n </div>","PeriodicalId":13172,"journal":{"name":"HLA","volume":"104 4","pages":""},"PeriodicalIF":5.9000,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A Novel HLA-DPA1 Allele, HLA-DPA1*01:204, Was Identified by Next-Generation Sequencing\",\"authors\":\"Xiong-jie He, Kun-Xiang Wang, Peng Zhang, Ti-Long Huang, Xian-Wen Zhang\",\"doi\":\"10.1111/tan.15710\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n <p><i>HLA-DPA1*01:204</i> has a single nucleotide substitution at position 426G > T when compared to the <i>HLA-DPA1*01:03:01:15</i> allele.</p>\\n </div>\",\"PeriodicalId\":13172,\"journal\":{\"name\":\"HLA\",\"volume\":\"104 4\",\"pages\":\"\"},\"PeriodicalIF\":5.9000,\"publicationDate\":\"2024-10-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"HLA\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1111/tan.15710\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CELL BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"HLA","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/tan.15710","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CELL BIOLOGY","Score":null,"Total":0}
引用次数: 0
摘要
与 HLA-DPA1*01:03:01:15 等位基因相比，HLA-DPA1*01:204 在 426G > T 位置有一个单核苷酸替换。
期刊介绍：
HLA, the journal, publishes articles on various aspects of immunogenetics. These include the immunogenetics of cell surface antigens, the ontogeny and phylogeny of the immune system, the immunogenetics of cell interactions, the functional aspects of cell surface molecules and their natural ligands, and the role of tissue antigens in immune reactions. Additionally, the journal covers experimental and clinical transplantation, the relationships between normal tissue antigens and tumor-associated antigens, the genetic control of immune response and disease susceptibility, and the biochemistry and molecular biology of alloantigens and leukocyte differentiation. Manuscripts on molecules expressed on lymphoid cells, myeloid cells, platelets, and non-lineage-restricted antigens are welcomed. Lastly, the journal focuses on the immunogenetics of histocompatibility antigens in both humans and experimental animals, including their tissue distribution, regulation, and expression in normal and malignant cells, as well as the use of antigens as markers for disease.
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