检测林奇综合征结直肠肿瘤的粪便挥发性有机化合物--前瞻性纵向多中心研究

IF 6.6 1区医学 Q1 GASTROENTEROLOGY & HEPATOLOGY Alimentary Pharmacology & Therapeutics Pub Date : 2024-10-18 DOI:10.1111/apt.18328

Elsa L. S. A. van Liere, Dewkoemar Ramsoekh, Emma Daulton, Maya Dakkak, Joris M. van Lingen, Trenton K. Stewart, Sofie Bosch, Beatriz Carvalho, Evelien Dekker, Maarten A. J. M. Jacobs, Jan Jacob Koornstra, Johan P. Kuijvenhoven, Monique E. van Leerdam, Tim G. J. de Meij, Gerrit A. Meijer, Manon C. W. Spaander, James A. Covington, Nanne K. H. de Boer

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引用次数: 0

摘要

无创生物标志物可降低林奇综合征患者结肠镜检查后的结直肠癌（CRC）发病率和结肠镜检查的过度使用。与粪便免疫化学检验（FIT）不同，粪便挥发性有机化合物（VOC）可准确检测晚期和非晚期结直肠肿瘤。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Faecal Volatile Organic Compounds to Detect Colorectal Neoplasia in Lynch Syndrome—A Prospective Longitudinal Multicentre Study

Non-invasive biomarkers may reduce post-colonoscopy colorectal cancer (CRC) rates and colonoscopy overuse in Lynch syndrome. Unlike faecal immunochemical test (FIT), faecal volatile organic compounds (VOCs) may accurately detect both advanced and non-advanced colorectal neoplasia.

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来源期刊

Alimentary Pharmacology & Therapeutics 医学-胃肠肝病学

CiteScore

15.60

自引率

7.90%

发文量

527

审稿时长

3-6 weeks

期刊介绍： Alimentary Pharmacology & Therapeutics is a global pharmacology journal focused on the impact of drugs on the human gastrointestinal and hepato-biliary systems. It covers a diverse range of topics, often with immediate clinical relevance to its readership.