法国艾滋病病毒/乙型肝炎病毒联合感染者的肝肺部 Mpox 病变

IF 7.2 2区医学 Q1 IMMUNOLOGY Emerging Infectious Diseases Pub Date : 2024-10-20 DOI:10.3201/eid3011.241331

Ruxandra Calin, Claire Périllaud-Dubois, Stéphane Marot, Khaldoun Kerrou, Gilles Peytavin, Marwa Bachir, Anne Laure Kirch, Ludovic Lassel, Vincent Fallet, Joel Gozlan, Jean Baptiste Pain, Patricia Senet, Olivier Ferraris, Sébastien Bine, Mathieu Hubert, Olivier Schwartz, Laurence Morand-Joubert, Gilles Pialoux

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引用次数: 0

摘要

我们报告了一例法国的艾滋病毒/乙型肝炎病毒联合感染者在<6个月内出现的持续性播散性肺炎，该患者有<200个CD4+细胞/mm3、肺部和肝脏坏死病变、持续性病毒血症和鼻咽排泄物。经过 90 天的替考韦利马特治疗和人疫苗免疫球蛋白注射后，临床疗效良好。

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Mpox Hepatic and Pulmonary Lesions in HIV/Hepatitis B Virus Co-Infected Patient, France

We report a case of persistent disseminated mpox evolving over >6 months in an HIV/hepatitis B virus co-infected patient in France who had <200 CD4+ cells/mm³, pulmonary and hepatic necrotic lesions, persistent viremia, and nasopharyngeal excretion. Clinical outcome was favorable after 90 days of tecovirimat treatment and administration of human vaccinia immunoglobulins.

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来源期刊

Emerging Infectious Diseases 医学-传染病学

CiteScore

17.30

自引率

1.70%

发文量

505

审稿时长

1 months

期刊介绍： Emerging Infectious Diseases is a monthly open access journal published by the Centers for Disease Control and Prevention. The primary goal of this peer-reviewed journal is to advance the global recognition of both new and reemerging infectious diseases, while also enhancing our understanding of the underlying factors that contribute to disease emergence, prevention, and elimination. Targeted towards professionals in the field of infectious diseases and related sciences, the journal encourages diverse contributions from experts in academic research, industry, clinical practice, public health, as well as specialists in economics, social sciences, and other relevant disciplines. By fostering a collaborative approach, Emerging Infectious Diseases aims to facilitate interdisciplinary dialogue and address the multifaceted challenges posed by infectious diseases.