提高核苷酸类似物停药后的功能性治愈率:peg-IFN 是答案吗?

IF 33 1区 医学 Q1 GASTROENTEROLOGY & HEPATOLOGY Journal of Hepatology Pub Date : 2025-02-01 Epub Date: 2024-10-22 DOI:10.1016/j.jhep.2024.10.019
Edo J. Dongelmans , Milan J. Sonneveld , Harry L.A. Janssen
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引用次数: 0

摘要

章节片段临床试验编号:不适用。利益冲突:Edo Dongelmans 没有利益冲突;Milan Sonneveld 从罗氏、百时美施贵宝、吉利德科学公司和 Fujirebio 获得演讲费和研究支持。Harry Janssen 从以下公司获得资助:吉利德科学公司、葛兰素史克公司、杨森公司、罗氏公司、Vir 生物技术公司,并担任以下公司的顾问:作者贡献:Edo Dongelmans,医学博士(构思:Equal;写作-原稿:Lead)。Milan Sonneveld,医学博士(构思:等同;写作 - 审稿 & 编辑:等同)。Harry L.A. Janssen, MD, PhD(构思:等同;指导:等同):平等;指导:撰写-审核-编辑:相同):核苷酸类似物(NA)在抑制慢性乙型肝炎(CHB)患者的 HBV DNA 方面耐受性好、疗效高。遗憾的是,HCC 的风险可能持续存在,尤其是在未达到功能性治愈(即 HBsAg 消失)的患者中。由于 NA 单一疗法很少能实现功能性治愈1 ,因此人们开始探索其他策略来提高 HBsAg 清除率。
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Increasing functional cure rates after nucleo(s)tide analogue withdrawal: Is peg-IFN the answer?
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来源期刊
Journal of Hepatology
Journal of Hepatology 医学-胃肠肝病学
CiteScore
46.10
自引率
4.30%
发文量
2325
审稿时长
30 days
期刊介绍: The Journal of Hepatology is the official publication of the European Association for the Study of the Liver (EASL). It is dedicated to presenting clinical and basic research in the field of hepatology through original papers, reviews, case reports, and letters to the Editor. The Journal is published in English and may consider supplements that pass an editorial review.
期刊最新文献
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