Elena Domínguez-Jurado , Agustín Lara-Sánchez , Iván Bravo , Alberto Ocaña , Carlos Alonso-Moreno
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State of the art in organometallic ruthenium metallodrugs for breast cancer treatment: Advances and innovations
Cancer is a major health concern and a leading cause of death worldwide. Among all cancer types, breast cancer has the highest incidence rate. The treatment of breast cancer encompasses the use of different drugs, with ruthenium metallodrugs emerging as promising alternatives to platinum derivatives. In this context, organometallic ruthenium(II) compounds are currently the most widely explored.
This review compiles all the organometallic ruthenium compounds described in the literature to date for the treatment of breast cancer. Additionally, it covers the use of ruthenium-based metallodrugs in combination therapy, phototherapy, and nanotechnology.
期刊介绍：
Coordination Chemistry Reviews offers rapid publication of review articles on current and significant topics in coordination chemistry, encompassing organometallic, supramolecular, theoretical, and bioinorganic chemistry. It also covers catalysis, materials chemistry, and metal-organic frameworks from a coordination chemistry perspective. Reviews summarize recent developments or discuss specific techniques, welcoming contributions from both established and emerging researchers.
The journal releases special issues on timely subjects, including those featuring contributions from specific regions or conferences. Occasional full-length book articles are also featured. Additionally, special volumes cover annual reviews of main group chemistry, transition metal group chemistry, and organometallic chemistry. These comprehensive reviews are vital resources for those engaged in coordination chemistry, further establishing Coordination Chemistry Reviews as a hub for insightful surveys in inorganic and physical inorganic chemistry.
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