大西洋人口中机器人辅助冠状动脉旁路移植手术的结果--文献的系统回顾和荟萃分析。

IF 4.3 3区 材料科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC ACS Applied Electronic Materials Pub Date : 2024-09-29 Epub Date: 2024-09-24 DOI:10.21037/acs-2024-rcabg-15
Ashley R Wilson-Smith, Christian J Wilson-Smith, Jemilla Strode Smith, Rowen Osborn, Winky Lo, Dominic Ng, Bridget Hwang, Justin Shaw, Benjamin T Muston, Michael L Williams, Aditya Eranki, Aashray Gupta, Lucy Manuel, Malgorzata Szpytma, Luca Borruso, Advait Pandya, David Downes
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引用次数: 0

摘要

背景:冠状动脉旁路移植术(CABG)在六十年的临床实践中大大降低了缺血性心脏病患者的发病率和死亡率。近年来,微创技术得到越来越多的描述和应用,有望为患者提供相同标准的治疗,而无需传统的全胸骨切开术,在某些情况下也无需心肺旁路,从而改善了恢复指标。本系统综述和荟萃分析旨在确定在大西洋病人群中接受机器人辅助 CABG 的所有病人的疗效:本系统综述和荟萃分析的方法符合系统综述和荟萃分析首选报告项目(PRISMA)声明。使用适当的检索术语检索了四个数据库。根据情况使用比例或平均值进行了 Meta 分析,并按照惯例进行了表述。Kaplan-Meier 曲线采用之前报道过的有效技术进行数字化和汇总。对每项研究的质量评估和偏倚风险进行了系统评估。根据既定的技术定义对患者人群进行了细分:通过文献检索确定了 35 项研究,其中 3 项研究的分组适合进行单独分析(最多可获得 42 个数据点)。在整个研究期间,共发现了 9078 名患者(69% 为男性),平均年龄为 62.3 岁。根据精算评估,1年、2年、3年、4年和5年的生存率分别为95%、94%、92%、90%和88%:本系统综述和荟萃分析表明,大西洋人口的短期死亡率、手术时间和入院[重症监护室(ICU)和总住院时间]结果令人鼓舞。对一个较小群体的长期死亡率评估结果令人鼓舞。本分析的一个主要注意事项是数据报告的高度异质性。对未来随机对照试验的分析对于确定这些程序的普遍性至关重要。
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The outcomes of robotic-assisted coronary artery bypass grafting surgery in the Atlantic demographic-a systematic review and meta-analysis of the literature.

Background: Coronary artery bypass grafting (CABG) has significantly reduced the morbidity and mortality of patients suffering from ischemic heart disease over its six decades of practice. In recent years, minimally invasive techniques have been increasingly described and utilized, with the promise of providing patients with the same standard of care without the need for the traditional full sternotomy, and in select cases without cardiopulmonary bypass, and thus providing improved recovery metrics. The present systematic review and meta-analysis sought to determine the outcomes of all patients receiving robotic-assisted CABG in an Atlantic patient demographic.

Methods: The methods for this systematic review and meta-analysis adhered to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) statement. Four databases were searched, using appropriate search terminology. Meta-analysis using proportions or means, as appropriate, were applied, and were presented as per routine practice. Kaplan-Meier curves were digitized and aggregated using previously reported, validated techniques. Quality assessment and risk of bias of each study were assessed systematically. Patient populations were subcategorized as per established technical definitions.

Results: Thirty-five studies were identified through the literature search, with three studies having subgroupings appropriate for separate analysis (yielding 42 data points maximally). A total of 9,078 patients (69% male), with a mean age of 62.3 years, were identified across the study period. On actuarial assessment, survival at yearly assessment from 1-, 2-, 3-, 4- and 5-yearly intervals was determined to be 95%, 94%, 92%, 90%, and 88%, respectively.

Conclusions: The present systematic review and meta-analysis demonstrated that short-term mortality, operative time, and admission [intensive care unit (ICU) and overall length of stay] outcomes were encouraging in the Atlantic demographic. Freedom from long-term mortality assessment of a smaller cohort showed encouraging results. A major caveat to the present analysis is the high degree of heterogeneity in the reporting of data. Analysis of future randomized controlled trials will be vital in establishing these procedures as commonplace.

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