磁性括约肌增强术和尼森胃底折叠术治疗胃食管反流病的比较研究。

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2024-12-01 Epub Date: 2024-10-14 DOI:10.1007/s10029-024-03172-z
Zhihao Zhu, Jinlei Mao, Menghui Zhou, Minjun Xia, Junjie Wu, Qi Chen, Fei Zhao, Hongxia Liang, Zhifei Wang
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引用次数: 0

摘要

简介磁性括约肌增强术(MSA)是一种新型外科技术,全球许多临床机构都在研究这种技术。与药物疗法相比,磁性括约肌增强术具有更好的疗效,因此于2012年被批准用于治疗胃食管反流病(GERD)。本研究旨在探讨 MSA 与腹腔镜尼森胃底折叠术(LNF)治疗胃食管反流病的安全性和有效性:方法:对术前接受 MSA 和 LNF 匹配特征治疗的 40 例患者进行回顾性分析。结果:胃食管反流症状明显改善:结果:在一年的手术随访中,MSA 和 LNF 患者的胃食管反流症状均有明显改善。吞咽困难是两种手术中常见的术后并发症,但没有病例需要进行内镜扩张。与 LNF 相比,MSA 的手术时间明显更短(112 分钟对 175 分钟,P):总之,LNF 和 MSA 都是安全且成功的胃食管反流手术疗法。MSA 的优点包括缩短手术时间、术后营养恢复更快以及保留打嗝能力。然而,这两种手术都普遍存在术后吞咽困难的问题,这就强调了改善术前沟通的重要性。在选择两种手术技术时,考虑与每种手术相关的术后症状至关重要。
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A comparative study of magnetic sphincter augmentation and Nissen fundoplication in the management of GERD.

Introduction: Magnetic sphincter augmentation (MSA) is a novel surgical technique investigated at many clinical institutes worldwide. In 2012, it received approval for treating Gastroesophageal reflux disease (GERD) because of its superior benefits compared to drug therapies. This study aimed to explore the safety and efficacy of MSA compared with Laparoscopic Nissen fundoplication (LNF) for GERD treatment.

Methods: A retrospective analysis was conducted on 40 patients who received preoperative matching features of MSA and LNF. The surgical details and one-year postoperative outcomes were analyzed and reported.

Results: Significant improvement in GERD symptoms was observed in both MSA and LNF patients over the one-year surgical follow-up. Dysphagia was a common postoperative complication observed in both procedures, but no cases required endoscopic dilation. MSA had a significantly shorter operative time compared to LNF (112 vs.175 min, P < 0.001), with faster postoperative dietary recovery [1(0.5,1.5) vs. 3(1.63,5.38) month(s), P < 0.001] and more preservation of hiccup ability (87.5% vs. 45.83%, P = 0.01). No significant disparities were observed between the two groups regarding hospital duration, recovery of physical strength, and upper gastrointestinal complaints.

Conclusion: In conclusion, both LNF and MSA are safe and successful surgical therapies for GERD. The benefits of MSA include reduced surgical time, quicker nutritional recovery following surgery, and preservation of hiccup capacity. However, with both surgeries, postoperative dysphagia is a prevalent problem that emphasizes the significance of improving preoperative communication. When selecting between two surgical techniques, it is crucial to consider the postoperative symptoms associated with each procedure.

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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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