具有抗呼吸道合胞病毒(RSV)病毒活性的天然产品和衍生物的最新进展。

IF 1.3 3区 医学 Q3 CHEMISTRY, APPLIED Journal of Asian Natural Products Research Pub Date : 2024-10-19 DOI:10.1080/10286020.2024.2417211
Ameena Tur Rasool, Erguang Li, Ahsan Nazir
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引用次数: 0

摘要

呼吸道合胞病毒(RSV)是一种广泛传播的病毒感染,每年导致数百万人患上高危疾病。人参根、紫锥菊和黄芪等药草通过防止病毒粘附、合胞体发育、抑制病毒内化、缓解呼吸道炎症、增强免疫系统和刺激干扰素释放,对抗病毒活性有积极作用。文中讨论了天然产品在降低成本、改善患者疗效和减少不良反应方面的潜在益处。本综述探讨了利用天然成分预防和控制 RSV 的现有证据以及临床实践中的挑战和机遇。
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Recent advances in natural products and derivatives with antiviral activity against respiratory syncytial virus (RSV).

Respiratory syncytial virus (RSV) is a widespread viral infection that causes millions of high-risk illnesses annually. Medicinal herbs such as ginseng root, echinacea purpurea, and radix astragali have a positive effect on antiviral activity by preventing viral adhesion, syncytial development, inhibiting viral internalization, relieving respiratory inflammation, strengthening the immune system, and stimulating the release of interferons. The potential benefits of natural products in terms of lower costs, better patient outcomes, and fewer adverse effects are discussed. This review examines the current evidence on the prevention and control of RSV with natural ingredients and the challenges and opportunities in clinical practice.

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来源期刊
CiteScore
3.20
自引率
5.90%
发文量
47
审稿时长
2.3 months
期刊介绍: The Journal of Asian Natural Products Research (JANPR) publishes chemical and pharmaceutical studies in the English language in the field of natural product research on Asian ethnic medicine. The journal publishes work from scientists in Asian countries, e.g. China, Japan, Korea and India, including contributions from other countries concerning natural products of Asia. The journal is chemistry-orientated. Major fields covered are: isolation and structural elucidation of natural constituents (including those for non-medical uses), synthesis and transformation (including biosynthesis and biotransformation) of natural products, pharmacognosy, and allied topics. Biological evaluation of crude extracts are acceptable only as supporting data for pure isolates with well-characterized structures. All published research articles in this journal have undergone rigorous peer review, based on initial editor screening and anonymized refereeing by at least two expert referees.
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