诊断出标准腊肠犬患有 III 型 von Willebrand 病。

IF 1.7 2区 农林科学 Q2 VETERINARY SCIENCES Journal of Small Animal Practice Pub Date : 2024-10-22 DOI:10.1111/jsap.13798
J Wait, K Clarke
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引用次数: 0

摘要

III 型 von Willebrand 病是一种罕见的凝血病,目前仅有关于荷兰库伊克猎犬、设德兰牧羊犬、切萨皮克湾寻回犬和苏格兰梗犬这四个犬种的公开报道。一只 2 岁零 9 个月大的雄性阉割标准腊肠犬因低血容量休克和颈部腹侧肿块就诊。据报告,该犬曾在例行阉割后发生过一次出血。住院期间,患者的充盈细胞容积从 27% 降至 15%,计算机断层扫描发现腹侧颈部有积液变化,推测为出血。在颅纵隔内还发现了一个类似的病灶。患者接受了等渗晶体液(哈特曼溶液)、合成胶体(凝胶体)以及血液制品(红细胞和新鲜冰冻血浆)的综合治疗。冯-维勒布兰德因子抗原检测证实了 III 型冯-维勒布兰德病。患者完全康复。该报告首次描述了标准腊肠犬的 III 型 von Willebrand 病。
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Diagnosis of type III von Willebrand disease in a standard dachshund.

Type III von Willebrand disease is a rare coagulopathy, with published reports only existing for four canine breeds - Dutch Kooiker Hounds, Shetland Sheepdogs, Chesapeake Bay Retrievers and Scottish Terriers. A 2-year and 9-month-old male neutered standard dachshund was presented for hypovolaemic shock and a ventral neck mass. One previous bleeding episode following routine castration was reported. The patient's packed cell volume fell from 27% to 15% during hospitalisation, and computed tomography identified changes to the ventral neck consistent with fluid accumulation, assumed to represent haemorrhage. A further, similar lesion was identified within the cranial mediastinum. The patient was managed with a combination of isotonic crystalloids (Hartmann's solution), synthetic colloid (Geloplasma), alongside administration of blood products (packed red blood cells and fresh frozen plasma). A Von Willebrand factor antigen assay confirmed Type III von Willebrand disease. The patient made a full recovery. This report is the first to describe Type III von Willebrand disease in a standard dachshund.

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来源期刊
Journal of Small Animal Practice
Journal of Small Animal Practice 农林科学-兽医学
CiteScore
3.30
自引率
6.20%
发文量
117
审稿时长
12-24 weeks
期刊介绍: Journal of Small Animal Practice (JSAP) is a monthly peer-reviewed publication integrating clinical research papers and case reports from international sources, covering all aspects of medicine and surgery relating to dogs, cats and other small animals. These papers facilitate the dissemination and implementation of new ideas and techniques relating to clinical veterinary practice, with the ultimate aim of promoting best practice. JSAP publishes high quality original articles, as well as other scientific and educational information. New developments are placed in perspective, encompassing new concepts and peer commentary. The target audience is veterinarians primarily engaged in the practise of small animal medicine and surgery. In addition to original articles, JSAP will publish invited editorials (relating to a manuscript in the same issue or a topic of current interest), review articles, which provide in-depth discussion of important clinical issues, and other scientific and educational information from around the world. The final decision on publication of a manuscript rests with the Editorial Board and ultimately with the Editor. All papers, regardless of type, represent the opinion of the authors and not necessarily that of the Editor, the Association or the Publisher. The Journal of Small Animal Practice is published on behalf of the British Small Animal Veterinary Association and is also the official scientific journal of the World Small Animal Veterinary Association
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