CT引导下冷冻消融术作为治疗无症状腰椎滑膜囊肿的一种新方法的长期有效性和可行性。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-10-15 DOI:10.1007/s00256-024-04808-y
Manraj K S Heran, Emmanuel Kodwo Yamoah Jackson, Nerses Nersesyan, Michael G Craig, Charles G Fisher, Marlise P Dos Santos
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引用次数: 0

摘要

目的:对 CT 引导下冷冻消融术用于微创治疗症状性腰椎面关节滑膜囊肿的病例进行长期随访,平均随访 38 个月(15-55 个月):我们在一家医疗机构开展了一项回顾性、非对照临床病例系列研究,研究对象是在 CT 引导下接受冷冻消融术治疗难治性或不适合影像引导下破裂术治疗的无症状腰椎面关节滑膜囊肿患者。有两例患者在两周内接受了冷冻消融术和囊肿破裂术。随访结束前,患者均接受了术后放射学检查和临床检查。部分患者接受了手术后的临床、CT 和 MRI 检查,并在随访结束前进行了复查。脊柱外科团队对所有患者进行了临床评估和评价。技术成功是指患者症状完全消失:我们治疗了 3 名女性和 3 名男性(平均年龄 64 岁)。四名患者的囊肿位于 L4-L5,其余两名患者的囊肿位于 L5-S1。我们为五名患者使用了两个冷冻探针,为一名患者使用了三个冷冻探针。所有病例都取得了临床和/或技术上的成功(平均随访 38 个月(15-55 个月))。我们没有发现与冷冻消融术本身有关的重大并发症:我们在 CT 引导下对有症状的腰椎面滑膜囊肿进行冷冻消融治疗的初步经验说明,在治疗此类病变时,手术是一种创伤较小的替代治疗方案。我们的长期治疗结果显示,复发率和并发症发生率都很低。CT引导下的冷冻消融术可能是治疗难治性腰椎滑膜囊肿的一种合理的替代方法,或者是破裂手术的禁忌症,或者是手术治疗不可行的腰椎滑膜囊肿。
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Long-term effectiveness and feasibility of CT-guided cryoablation as a novel treatment option for symptomatic lumbar synovial cysts.

Objective: To present a case series with a long-term follow-up of CT-guided cryoablation procedure for the minimally invasive treatment of symptomatic lumbar facet synovial cyst with a mean follow-up of 38 months (range, 15-55).

Materials and methods: We present a retrospective, uncontrolled clinical case series in a single institution on patients treated with CT-guided cryoablation for symptomatic lumbar facet joint synovial cyst refractory to or not suitable for imaging-guided rupture procedure. In two cases, patients underwent cryoablation and cyst rupture within a 2-week period. Outcome measures were post-procedural radiologic studies and clinical examinations up to the end of the follow-up. Selected patients underwent post-procedural clinical and CT and MRI imaging which were reviewed up to the conclusion of the follow-up. All patients were clinically assessed and evaluated by spine surgery team. Technical success was complete resolution of patient's symptoms.

Results: We treated 3 females and 3 males (mean age 64 years). Four patients had cysts located at L4-L5, and the remaining two at L5-S1. We used two cryoprobes in five patients, and three in one. Clinical and/or technical success was documented in all cases (mean follow-up, 38 months [range, 15-55]). We found no major complications related to the cryoablation itself.

Conclusion: Our initial experience with CT-guided cryoablation for symptomatic lumbar facet synovial cysts describes a less invasive alternative treatment option to surgery for the management of such lesions. Our long-term outcome experience showed low recurrence and complication rates. CT-guided cryoablation may be a reasonable alternative approach to treat lumbar synovial cysts that are refractory or contraindicated to the rupture procedure and where surgical management is unfeasible.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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