脊髓损伤压迫伤后骨髓炎的发生频率:系统回顾和荟萃分析。

IF 0.7 Q4 CLINICAL NEUROLOGY Spinal Cord Series and Cases Pub Date : 2024-10-14 DOI:10.1038/s41394-024-00685-8
Ehsan Jangholi, Seyed Danail Alizadeh, Farzin Farahbakhsh, Vali Baigi, Zahra Ghodsi, Pouya Mahdavi Sharif, Shahriar Ghashghaei, Mahkameh Abbaszadeh, Arman Zeinaddini Meymand, Zahra Eskandari, Vafa Rahimi-Movaghar
{"title":"脊髓损伤压迫伤后骨髓炎的发生频率:系统回顾和荟萃分析。","authors":"Ehsan Jangholi, Seyed Danail Alizadeh, Farzin Farahbakhsh, Vali Baigi, Zahra Ghodsi, Pouya Mahdavi Sharif, Shahriar Ghashghaei, Mahkameh Abbaszadeh, Arman Zeinaddini Meymand, Zahra Eskandari, Vafa Rahimi-Movaghar","doi":"10.1038/s41394-024-00685-8","DOIUrl":null,"url":null,"abstract":"<p><strong>Study design: </strong>A systematic review and meta-analysis OBJECTIVE: To determine the global frequency of osteomyelitis in individuals with spinal cord injury who have pressure injuries (SCI-PI).</p><p><strong>Methods: </strong>A comprehensive search on PubMed, EMBASE, Scopus, and the Web of Science has been conducted until November 2023. The Cochrane Handbook for Systematic Reviews was followed. Cohort and cross-sectional studies included SCI-PI participants who reported the frequency of osteomyelitis without language restriction. Data extraction was performed by four reviewers in two groups. We used the Newcastle-Ottawa Quality Assessment Scale for quality assessment. The Chi-squared and I<sup>2</sup> tests were applied to detect heterogeneity between studies. Also, a random-effects model was performed for the report data.</p><p><strong>Results: </strong>Ten out of 986 studies met our eligibility criteria, with 492 SCI-PI individuals. It was discovered that most SCIs were thoracolumbar injuries and male. There was a history of PI in more than half the patients. SCI was primarily caused by trauma. A meta-analysis revealed a significantly heterogeneous 43.0% osteomyelitis frequency. There was no evidence of publication bias. Subgroup analysis based on study quality revealed that the frequency of osteomyelitis in low-quality studies was 34.5%, whereas the frequency in high-quality research was 47.4%. Furthermore, the overall frequency of osteomyelitis was 29.0% in the subgroup analysis of research carried out in the USA.</p><p><strong>Conclusions: </strong>Our study highlights the significant burden of osteomyelitis among SCI-PI individuals. These findings underscore the pressing need for standardized diagnostic and management protocols to mitigate the morbidity associated with osteomyelitis in this vulnerable population.</p>","PeriodicalId":22079,"journal":{"name":"Spinal Cord Series and Cases","volume":null,"pages":null},"PeriodicalIF":0.7000,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11473765/pdf/","citationCount":"0","resultStr":"{\"title\":\"The frequency of osteomyelitis after pressure injury in spinal cord injury: a systematic review and meta-analysis.\",\"authors\":\"Ehsan Jangholi, Seyed Danail Alizadeh, Farzin Farahbakhsh, Vali Baigi, Zahra Ghodsi, Pouya Mahdavi Sharif, Shahriar Ghashghaei, Mahkameh Abbaszadeh, Arman Zeinaddini Meymand, Zahra Eskandari, Vafa Rahimi-Movaghar\",\"doi\":\"10.1038/s41394-024-00685-8\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Study design: </strong>A systematic review and meta-analysis OBJECTIVE: To determine the global frequency of osteomyelitis in individuals with spinal cord injury who have pressure injuries (SCI-PI).</p><p><strong>Methods: </strong>A comprehensive search on PubMed, EMBASE, Scopus, and the Web of Science has been conducted until November 2023. The Cochrane Handbook for Systematic Reviews was followed. Cohort and cross-sectional studies included SCI-PI participants who reported the frequency of osteomyelitis without language restriction. Data extraction was performed by four reviewers in two groups. We used the Newcastle-Ottawa Quality Assessment Scale for quality assessment. The Chi-squared and I<sup>2</sup> tests were applied to detect heterogeneity between studies. Also, a random-effects model was performed for the report data.</p><p><strong>Results: </strong>Ten out of 986 studies met our eligibility criteria, with 492 SCI-PI individuals. It was discovered that most SCIs were thoracolumbar injuries and male. There was a history of PI in more than half the patients. SCI was primarily caused by trauma. A meta-analysis revealed a significantly heterogeneous 43.0% osteomyelitis frequency. There was no evidence of publication bias. Subgroup analysis based on study quality revealed that the frequency of osteomyelitis in low-quality studies was 34.5%, whereas the frequency in high-quality research was 47.4%. Furthermore, the overall frequency of osteomyelitis was 29.0% in the subgroup analysis of research carried out in the USA.</p><p><strong>Conclusions: </strong>Our study highlights the significant burden of osteomyelitis among SCI-PI individuals. These findings underscore the pressing need for standardized diagnostic and management protocols to mitigate the morbidity associated with osteomyelitis in this vulnerable population.</p>\",\"PeriodicalId\":22079,\"journal\":{\"name\":\"Spinal Cord Series and Cases\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2024-10-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11473765/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Spinal Cord Series and Cases\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1038/s41394-024-00685-8\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Spinal Cord Series and Cases","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1038/s41394-024-00685-8","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0

摘要

研究设计:系统综述和荟萃分析 目的:确定脊髓损伤压迫伤(SCI-PI)患者骨髓炎的全球发病率:方法:对 PubMed、EMBASE、Scopus 和 Web of Science 进行了全面检索,检索期至 2023 年 11 月。检索遵循《Cochrane 系统综述手册》。队列研究和横断面研究纳入了报告骨髓炎发生频率的 SCI-PI 参与者,没有语言限制。数据提取由四位审稿人分两组进行。我们采用纽卡斯尔-渥太华质量评估量表进行质量评估。采用Chi-squared和I2检验来检测研究之间的异质性。此外,我们还对报告数据采用了随机效应模型:在 986 项研究中,有 10 项符合我们的资格标准,共涉及 492 名 SCI-PI 患者。研究发现,大多数 SCI 为胸腰椎损伤,且多为男性。半数以上的患者有 PI 病史。SCI 主要由外伤引起。一项荟萃分析显示,骨髓炎的发生率为 43.0%,差异很大。没有证据表明存在发表偏倚。基于研究质量的分组分析显示,低质量研究中骨髓炎的发生率为34.5%,而高质量研究中骨髓炎的发生率为47.4%。此外,在对美国进行的研究进行的分组分析中,骨髓炎的总体发生率为29.0%:我们的研究凸显了骨髓炎给 SCI-PI 患者带来的沉重负担。这些研究结果突出表明,迫切需要制定标准化的诊断和管理方案,以降低骨髓炎在这一弱势群体中的发病率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
The frequency of osteomyelitis after pressure injury in spinal cord injury: a systematic review and meta-analysis.

Study design: A systematic review and meta-analysis OBJECTIVE: To determine the global frequency of osteomyelitis in individuals with spinal cord injury who have pressure injuries (SCI-PI).

Methods: A comprehensive search on PubMed, EMBASE, Scopus, and the Web of Science has been conducted until November 2023. The Cochrane Handbook for Systematic Reviews was followed. Cohort and cross-sectional studies included SCI-PI participants who reported the frequency of osteomyelitis without language restriction. Data extraction was performed by four reviewers in two groups. We used the Newcastle-Ottawa Quality Assessment Scale for quality assessment. The Chi-squared and I2 tests were applied to detect heterogeneity between studies. Also, a random-effects model was performed for the report data.

Results: Ten out of 986 studies met our eligibility criteria, with 492 SCI-PI individuals. It was discovered that most SCIs were thoracolumbar injuries and male. There was a history of PI in more than half the patients. SCI was primarily caused by trauma. A meta-analysis revealed a significantly heterogeneous 43.0% osteomyelitis frequency. There was no evidence of publication bias. Subgroup analysis based on study quality revealed that the frequency of osteomyelitis in low-quality studies was 34.5%, whereas the frequency in high-quality research was 47.4%. Furthermore, the overall frequency of osteomyelitis was 29.0% in the subgroup analysis of research carried out in the USA.

Conclusions: Our study highlights the significant burden of osteomyelitis among SCI-PI individuals. These findings underscore the pressing need for standardized diagnostic and management protocols to mitigate the morbidity associated with osteomyelitis in this vulnerable population.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Spinal Cord Series and Cases
Spinal Cord Series and Cases Medicine-Neurology (clinical)
CiteScore
2.20
自引率
8.30%
发文量
92
期刊最新文献
Non-surgical spinal cord infarction: case series & long-term follow-up of functional outcome. The frequency of osteomyelitis after pressure injury in spinal cord injury: a systematic review and meta-analysis. The clinical evolution of patients with idiopathic spinal cord herniation: a case series. Resting energy expenditure during spinal cord injury rehabilitation and utility of fat-free mass-based energy prediction equations: a pilot study. Epidemiology of traumatic spinal cord injury in Ireland, 2017-2022.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1