使用特殊设计的半硬质导管进行微创表面活性物质给药：一个中低收入国家三级新生儿科的经验。

IF 0.5 4区医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Tropical Doctor Pub Date : 2024-10-14 DOI:10.1177/00494755241288931

Sourabh Kumar, Pankaj Chaudhary, Mayank Priyadarshi, Suman Chaurasia, Poonam Singh, Sriparna Basu

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引用次数: 0

摘要

该研究回顾性收集了 74 例接受表面活性物质替代疗法（SRT）的早产新生儿的临床结果，以比较以下给药方式：(1) 通过特殊设计的半硬导管（Surfcath）进行微创表面活性物质给药（LISA）；(2) INtubate-SURfactant-Extubate (INSURE)；(3) 通过气管导管（ETT），用于需要机械通气的新生儿。月龄后 36 周时死亡或支气管肺发育不良（BPD）的主要复合结果在 LISA 组为 41%，在 INSURE 组为 38%，在 ETT 组为 77%（P＜0.05）。

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Less invasive surfactant administration with specially designed semirigid catheter: Experience from a tertiary level neonatal unit of a lower middle-income country.

Clinical outcomes of 74 preterm neonates, who received surfactant replacement therapy (SRT), were collected retrospectively, to compare the following modes of administration: (1) less invasive surfactant administration (LISA) via a specially designed semirigid catheter (Surfcath), (2) INtubate-SURfactant-Extubate (INSURE) and (3) through endotracheal tube (ETT), in neonates requiring mechanical ventilation. The primary composite outcome of mortality or bronchopulmonary dysplasia (BPD) at 36 weeks' post-menstrual age was 41% in LISA, 38% in INSURE and 77% in ETT groups (p < 0.01), the difference being mainly due to the high incidence of mortality in the latter. LISA, via a specially designed semirigid catheter, was safe and feasible in preterm neonates.

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来源期刊

Tropical Doctor 医学-公共卫生、环境卫生与职业卫生

CiteScore

1.20

自引率

0.00%

发文量

144

审稿时长

3 months

期刊介绍： The only journal written by and for health workers in low and middle-income countries, Tropical Doctor provides medical expertise and practical advice on how to apply current medical knowledge to the special circumstances of LMIC countries. This journal provides an ideal forum for sharing experiences and establishing best practice, aiding communication between medical professionals in different environments.