Tropical Doctor最新文献

Amyloidosis is a group of disorders with extracellular accumulation of autologous fibrillary insoluble proteins in various tissues and organs such as the kidneys, liver, spleen, heart, and gastrointestinal tract leading to impaired function. Renal amyloidosis is usually considered to be a progressive disease manifesting as nephrotic syndrome and renal insufficiency with tuberculosis being one of the most common causes in adults. However, the occurrence of similar associations is rarely described in children. We report a case of an 11-year old girl who presented with nephrotic syndrome and pulmonary tuberculosis and attained disease remission with successful treatment of tuberculosis.

We describe a case of scrub typhus in a 12-year old boy who presented with symptoms mimicking acute acalculous cholecystitis. He tested positive for anti-scrub typhus IgM antibodies. Treatment with oral azithromycin led to significant improvement and resolution of symptoms. Thus it is important to consider scrub typhus as a differential diagnosis for an acute abdomen in endemic areas. Timely diagnosis may avoid unnecessary suffering.

The incidence of pyogenic liver abscesses (PLAs) resulting from foreign body ingestion is relatively rare; however, it poses significant risks, necessitating timely diagnosis and intervention. This report presents an unusual case involving a 77-year-old female who developed a PLA following the ingestion of a fishbone. The patient was accurately diagnosed using high-resolution computed tomography-based three-dimensional reconstruction and subsequently underwent successful treatment through laparoscopic incision, drainage, and simultaneous removal of the fishbone.

The incidence of tuberculosis (TB) is increasing worldwide. Bone and joint TB are the most common types of extra-pulmonary TB, but can easily be misdiagnosed, since articular TB commonly mimics other joint diseases, including reactive and degenerative arthritis, and articular manifestations associated with systemic autoimmune diseases. Furthermore, patients with systemic auto-immune diseases are often more prone to mycobacterial infection. The diagnosis of joint TB can be made using a combination of the following methods: clinical evaluation, imaging, tuberculin skin test, interferon-gamma release assays, nucleic acid amplification tests, and Gene X-pert MTB/rifampicin assay.

This case report presents an instance of scrub typhus, distinguished by a solitary eschar on the thigh, and explores the application of dermoscopy with 365 nm ultraviolet illumination for real-time monitoring during treatment. Scrub typhus, caused by Orientia tsutsugamushi, typically manifests with eschars that can be easily overlooked due to their painless nature. This case highlights the utility of dermoscopy in improving eschar detection and therapeutic monitoring, offering a novel approach to managing this potentially severe disease.

Hyoscyamus niger, commonly known as henbane, contains potent alkaloids that can cause anticholinergic toxicity when ingested. This case report describes a 35-year-old male gardener who presented with confusion, hallucinations, dry mouth, and dilated pupils after consuming parts of the plant. The patient was treated with rehydration, activated charcoal, and physostigmine, leading to rapid clinical improvement. This case highlights the importance of recognizing plant-based poisonings and the efficacy of physostigmine in managing anticholinergic syndrome. Public awareness and education on the dangers of unfamiliar plants are essential to prevent accidental ingestions.

Strongyloides stercoralis infects the duodenum and jejunum with rare involvement of the stomach. However, the clinical presentation and endoscopic findings are non-specific. There are limited data on upper gastrointestinal endoscopy findings in S. stercoralis with gastroduodenal involvement. In this case series of seven patients, we summarize such findings after diagnosis with tissue biopsy.