Laura Mc Loughlin, Henry Zhang, Megan Blom, Michael Walsh, Tom Moran, Benjamin Dixon, Matthew Magarey, Fergal O'Duffy
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引用次数: 0
摘要
背景:经口机器人手术(TORS)舌扁桃体切除术在头颈部不明原发癌(CUP)诊断算法中的应用近年来越来越受欢迎。我们研究的主要目的是确定接受舌±腭扁桃体切除术进行头颈部 CUP 检查的人群中原发肿瘤的识别率:这是一项回顾性研究,研究对象是8年来在两个国家的四个中心接受诊断性TORS治疗头颈部CUP的所有患者:结果:共纳入 56 名接受 TORS 辅助诊断原发部位的患者。总的来说,TORS舌±腭扁桃体切除术确定了41例(73.2%)患者的原发肿瘤。半数以上为 T1 肿瘤,25% 的肿瘤大小在 10 毫米以下。在人乳头状瘤病毒(HPV)+结节病患者中,识别率为 82.6%:结论:TORS舌扁桃体切除术是 CUP 诊断工作的有效补充,尤其适用于那些有 HPV+结节病的患者。
The Role of Transoral Robotic Palatine and Lingual Tonsillectomy in the Diagnosis of Carcinoma of Unknown Primary in the Head and Neck Region.
Background: The use of transoral robotic surgery (TORS) lingual tonsillectomy in the diagnostic algorithm for head and neck carcinoma of unknown primary (CUP) has gained recent popularity. The primary aim of our study was to determine the identification rate of primary tumors in our cohort undergoing lingual ± palatine tonsillectomy for the workup of head and neck CUP.
Methods: This was a retrospective study of all patients undergoing diagnostic TORS for head and neck CUP over an eight-year period, across four centers in two countries.
Results: Fifty-six patients undergoing TORS to aid diagnosis of a primary site were included. Overall, TORS lingual ± palatine tonsillectomy identified a primary tumor in 41 (73.2%) patients. Over half were T1 tumors, with 25% measuring under 10 mm. Among those with human papilloma virus (HPV)+ nodal disease, the identification rate was 82.6%.
Conclusions: TORS lingual tonsillectomy is an effective addition to the diagnostic workup of CUP, particularly in those with HPV+ nodal disease.
期刊介绍:
Head & Neck is an international multidisciplinary publication of original contributions concerning the diagnosis and management of diseases of the head and neck. This area involves the overlapping interests and expertise of several surgical and medical specialties, including general surgery, neurosurgery, otolaryngology, plastic surgery, oral surgery, dermatology, ophthalmology, pathology, radiotherapy, medical oncology, and the corresponding basic sciences.